2023
Quantifying the Impact of Genetics on Neurocognition in Nonsyndromic Sagittal Craniosynostosis
Junn A, Dinis J, Long A, Timberlake A, Persing J, Alperovich M. Quantifying the Impact of Genetics on Neurocognition in Nonsyndromic Sagittal Craniosynostosis. Plastic & Reconstructive Surgery 2023, 152: 300e-306e. PMID: 36912936, DOI: 10.1097/prs.0000000000010400.Peer-Reviewed Original ResearchConceptsFull-scale intelligence quotientHigh-risk mutationsNonsyndromic craniosynostosisNeurocognitive outcomesDouble-blinded cohort studySignificant differencesCLINICAL QUESTION/LEVELVisuomotor integrationTime of surgeryType of surgeryHigh-risk genotypesPoor neurocognitive outcomesNonsyndromic sagittal craniosynostosisHigh-risk genesPresence of mutationsCohort studySurgery typePatient factorsNeurodevelopmental delayAnalysis of covarianceNeurocognitive testingNeurocognitive effectsPatientsSociodemographic factorsSagittal craniosynostosisLong-term neurocognitive outcomes in 204 single-suture craniosynostosis patients
Junn A, Long A, Hauc S, Almeida M, Alper D, Rivera J, Mayes L, Persing J, Alperovich M. Long-term neurocognitive outcomes in 204 single-suture craniosynostosis patients. Child's Nervous System 2023, 39: 1921-1928. PMID: 36877207, DOI: 10.1007/s00381-023-05908-1.Peer-Reviewed Original ResearchConceptsFull Scale IQVisuomotor integrationVisual perceptionVerbal IQNeurocognitive testingVisual perception scoresHigher scoresLong-term neurocognitive outcomesCognitive profileWhite matter connectionsNeurocognitive deficitsIQPerception scoresMean IQNeurocognitive outcomesFrontal lobeLower scoresMotor controlMotor coordinationPerceptionNon-syndromic craniosynostosisUnicoronal synostosisScoresChildren 6Neurocognitive Outcomes in Deformational Plagiocephaly: Is There an Association between Morphologic Severity and Results?
Park K, Chandler L, Ahmad M, Singh A, Allam O, Mets E, Bridgett D, Persing J, Alperovich M. Neurocognitive Outcomes in Deformational Plagiocephaly: Is There an Association between Morphologic Severity and Results? Plastic & Reconstructive Surgery 2023, 152: 488e-498e. PMID: 36847664, DOI: 10.1097/prs.0000000000010330.Peer-Reviewed Original ResearchConceptsNeurocognitive outcomesHelmet therapyDeformational plagiocephalyNeurocognitive functionLong-term neurocognitive functionCLINICAL QUESTION/LEVELLong-term neurocognitive outcomesWorse neurocognitive outcomesVisual-motor functionMotor coordination scoresHead shape abnormalitiesSeverity of plagiocephalyNeurodevelopmental effectsSchool-aged childrenDP cohortMotor coordinationSignificant laterality
2021
5: Long-term Follow-up of Pre-operative Infant Event-related Potential in Children with Craniosynostosis
Junn A, Dinis J, Reategui A, Yang J, Persing J, Alperovich M. 5: Long-term Follow-up of Pre-operative Infant Event-related Potential in Children with Craniosynostosis. Plastic & Reconstructive Surgery Global Open 2021, 9: 24-24. PMCID: PMC8312855, DOI: 10.1097/01.gox.0000770052.46608.c7.Peer-Reviewed Original ResearchEvent-related potentialsFull Scale IQPerformance IQNeurocognitive outcomesMath achievementMotor skillsInfants' event-related potentialsNeurocognitive testingSchool ageWhole-vault cranioplastyFine motor skillsMothers' high levelsFathers' high levelsLanguage stimuliN450 componentERP resultsAuditory processingERP recordingsNeurocognitive testsReading achievementERP assessmentAssessment of IQBrain activityNeurocognitive deficitsAcademic achievement
2019
S7A-13 SESSION 7A: SAGITTAL SYNOSTOSIS LONG-TERM NEUROCOGNITIVE OUTCOMES OF SPRING-ASSISTED SURGERY VERSUS CRANIAL VAULT REMODELING
Alperovich M, Runyan C, Gabrick K, Wu R, Morgan C, Park S, Chapman L, Couture D, David L, Persing J. S7A-13 SESSION 7A: SAGITTAL SYNOSTOSIS LONG-TERM NEUROCOGNITIVE OUTCOMES OF SPRING-ASSISTED SURGERY VERSUS CRANIAL VAULT REMODELING. Plastic & Reconstructive Surgery Global Open 2019, 7: 73-74. DOI: 10.1097/01.gox.0000583176.22812.8e.Peer-Reviewed Original Research