2023
Quantifying the Impact of Genetics on Neurocognition in Nonsyndromic Sagittal Craniosynostosis
Junn A, Dinis J, Long A, Timberlake A, Persing J, Alperovich M. Quantifying the Impact of Genetics on Neurocognition in Nonsyndromic Sagittal Craniosynostosis. Plastic & Reconstructive Surgery 2023, 152: 300e-306e. PMID: 36912936, DOI: 10.1097/prs.0000000000010400.Peer-Reviewed Original ResearchConceptsFull-scale intelligence quotientHigh-risk mutationsNonsyndromic craniosynostosisNeurocognitive outcomesDouble-blinded cohort studySignificant differencesCLINICAL QUESTION/LEVELVisuomotor integrationTime of surgeryType of surgeryHigh-risk genotypesPoor neurocognitive outcomesNonsyndromic sagittal craniosynostosisHigh-risk genesPresence of mutationsCohort studySurgery typePatient factorsNeurodevelopmental delayAnalysis of covarianceNeurocognitive testingNeurocognitive effectsPatientsSociodemographic factorsSagittal craniosynostosis
2011
Combined metopic and sagittal craniosynostosis: is it worse than sagittal synostosis alone?
Terner JS, Travieso R, Lee SS, Forte AJ, Patel A, Persing JA. Combined metopic and sagittal craniosynostosis: is it worse than sagittal synostosis alone? Neurosurgical FOCUS 2011, 31: e2. PMID: 21806341, DOI: 10.3171/2011.6.focus11100.Peer-Reviewed Original ResearchConceptsMonths of ageSmaller intracranial volumeBrain dysfunctionIntracranial volumeSagittal synostosisPatient groupVentricular volumeAge groupsSagittal craniosynostosisCSF spaceBrain volume reductionBrain tissue volumesSex-matched controlsSame age groupVolume reductionRetrospective chartFemale patientsForms of craniosynostosisSagittal synostosesPatientsYoung infantsBrain tissueCT reviewIntracranial compartmentDysfunction112: THE IMPACT OF THE AGE OF SURGERY AND TYPE OF SURGICAL INTERVENTION ON LONG-TERM NEUROPSYCHOLOGICAL OUTCOMES IN SAGITTAL CRANIOSYNOSTOSIS
Patel A, Terner J, Travieso R, Roginiel A, Alderman M, Bridgett D, Losee J, Pollack I, Kanev P, Persing J. 112: THE IMPACT OF THE AGE OF SURGERY AND TYPE OF SURGICAL INTERVENTION ON LONG-TERM NEUROPSYCHOLOGICAL OUTCOMES IN SAGITTAL CRANIOSYNOSTOSIS. Plastic & Reconstructive Surgery 2011, 127: 64. DOI: 10.1097/01.prs.0000396799.90560.60.Peer-Reviewed Original ResearchLong-term neuropsychological outcomesAge of surgerySurgical interventionNeuropsychological outcomesSagittal craniosynostosis
2010
Intracranial Compartment Volume Changes in Sagittal Craniosynostosis Patients: Influence of Comprehensive Cranioplasty
Lee SS, Duncan CC, Knoll BI, Persing JA. Intracranial Compartment Volume Changes in Sagittal Craniosynostosis Patients: Influence of Comprehensive Cranioplasty. Plastic & Reconstructive Surgery 2010, 126: 187-196. PMID: 20595867, DOI: 10.1097/prs.0b013e3181dab5be.Peer-Reviewed Original ResearchConceptsIntracranial compartment volumesSagittal synostosis patientsBrain tissue volumesGender-matched controlsBrain volumeCompartment volumeAge groupsSagittal craniosynostosis patientsTissue volumeMonths of ageConsecutive childrenCorrective surgeryTomographic scanRetrospective analysisPatientsTherapeutic objectivesCraniosynostosis patientsSagittal synostosisSagittal craniosynostosisPatient dataVolume enlargementAgeCranioplastyMonthsEquivalent increase