2022
Assessment of Sex Diversity Among Craniofacial Academic Faculty
Rivera J, Hauc S, Juan H, Williams M, Stögner V, Najafali D, Long A, Almeida M, Persing J, Alperovich M. Assessment of Sex Diversity Among Craniofacial Academic Faculty. Journal Of Craniofacial Surgery 2022, 34: 202-205. PMID: 36608098, DOI: 10.1097/scs.0000000000009109.Peer-Reviewed Original ResearchConceptsAmerican Cleft Palate-Craniofacial AssociationMaxillofacial surgeonsSignificant differencesAmerican SocietyCleft Palate-Craniofacial JournalFellowship programsSex disparitiesMultiple specialtiesSex diversityPlastic surgeryCraniofacial surgeryMedical specialtiesSurgery facultyYears of experienceSurgerySurgical residencySurgery journals
2019
Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis
Timberlake AT, Jin SC, Nelson-Williams C, Wu R, Furey CG, Islam B, Haider S, Loring E, Galm A, Steinbacher D, Larysz D, Staffenberg D, Flores R, Rodriguez E, Boggon T, Persing J, Lifton R, Lifton RP, Gunel M, Mane S, Bilguvar K, Gerstein M, Loring E, Nelson-Williams C, Lopez F, Knight J. Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 15116-15121. PMID: 31292255, PMCID: PMC6660739, DOI: 10.1073/pnas.1902041116.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAlpha CateninChildChild, PreschoolCraniosynostosesExomeExome SequencingFemaleGene ExpressionGlypicansHistone AcetyltransferasesHumansMaleMutationNuclear ProteinsPedigreeRisk AssessmentSignal TransductionSkullSOXC Transcription FactorsTranscription Factor AP-2Zinc Finger Protein Gli2ConceptsRare damaging mutationsSyndromic craniosynostosisCongenital anomaliesDamaging mutationsSyndromic casesExome sequencingAdditional congenital anomaliesFrequent congenital anomaliesDamaging de novo mutationsNeural crest cell migrationDamaging de novoCrest cell migrationCS patientsMutation burdenChromatin modifiersSubsequent childrenTranscription factorsDe novo mutationsCS casesCS geneHedgehog pathwayDisease locusPremature fusionFunction mutationsCraniosynostosis
2017
De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis
Timberlake AT, Furey CG, Choi J, Nelson-Williams C, Loring E, Galm A, Kahle K, Steinbacher D, Larysz D, Persing J, Lifton R, Bilguvar K, Mane S, Tikhonova I, Castaldi C, Knight J. De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: e7341-e7347. PMID: 28808027, PMCID: PMC5584457, DOI: 10.1073/pnas.1709255114.Peer-Reviewed Original ResearchConceptsBone morphogenetic proteinRas/ERKDe novo mutationsNovo mutationsRas/ERK pathwayDamaging de novo mutationsHigh locus heterogeneityRare syndromic diseaseCommon risk variantsInhibitor of WntSyndromic craniosynostosesNew genesParent-offspring triosSyndromic diseaseMorphogenetic proteinsNegative regulatorERK pathwayMore cranial suturesGenesMidline craniosynostosisRisk variantsWntLocus heterogeneityMutationsExome sequencing
2012
Improved Correction of Supraorbital Rim Deformity in Craniosynostosis by the “Tilt” Procedure
Patel A, Chang CC, Terner JS, Tuggle CT, Persing JA. Improved Correction of Supraorbital Rim Deformity in Craniosynostosis by the “Tilt” Procedure. Journal Of Craniofacial Surgery 2012, 23: 370-373. PMID: 22421828, DOI: 10.1097/scs.0b013e318240fac8.Peer-Reviewed Original Research
2011
Combined metopic and sagittal craniosynostosis: is it worse than sagittal synostosis alone?
Terner JS, Travieso R, Lee SS, Forte AJ, Patel A, Persing JA. Combined metopic and sagittal craniosynostosis: is it worse than sagittal synostosis alone? Neurosurgical FOCUS 2011, 31: e2. PMID: 21806341, DOI: 10.3171/2011.6.focus11100.Peer-Reviewed Original ResearchConceptsMonths of ageSmaller intracranial volumeBrain dysfunctionIntracranial volumeSagittal synostosisPatient groupVentricular volumeAge groupsSagittal craniosynostosisCSF spaceBrain volume reductionBrain tissue volumesSex-matched controlsSame age groupVolume reductionRetrospective chartFemale patientsForms of craniosynostosisSagittal synostosesPatientsYoung infantsBrain tissueCT reviewIntracranial compartmentDysfunction
2010
Plastic Surgery during Natural Disasters: Lessons from Haiti
Patel A, Mcrae M, Mcrae M, Sinha I, Persing J. Plastic Surgery during Natural Disasters: Lessons from Haiti. Plastic & Reconstructive Surgery 2010, 126: 111e. PMID: 20679815, DOI: 10.1097/prs.0b013e3181df7255.Peer-Reviewed Original ResearchIntracranial Compartment Volume Changes in Sagittal Craniosynostosis Patients: Influence of Comprehensive Cranioplasty
Lee SS, Duncan CC, Knoll BI, Persing JA. Intracranial Compartment Volume Changes in Sagittal Craniosynostosis Patients: Influence of Comprehensive Cranioplasty. Plastic & Reconstructive Surgery 2010, 126: 187-196. PMID: 20595867, DOI: 10.1097/prs.0b013e3181dab5be.Peer-Reviewed Original ResearchConceptsIntracranial compartment volumesSagittal synostosis patientsBrain tissue volumesGender-matched controlsBrain volumeCompartment volumeAge groupsSagittal craniosynostosis patientsTissue volumeMonths of ageConsecutive childrenCorrective surgeryTomographic scanRetrospective analysisPatientsTherapeutic objectivesCraniosynostosis patientsSagittal synostosisSagittal craniosynostosisPatient dataVolume enlargementAgeCranioplastyMonthsEquivalent increaseComplication Rates of Lipoabdominoplasty versus Traditional Abdominoplasty in High-Risk Patients
Samra S, Sawh-Martinez R, Barry O, Persing JA. Complication Rates of Lipoabdominoplasty versus Traditional Abdominoplasty in High-Risk Patients. Plastic & Reconstructive Surgery 2010, 125: 683-690. PMID: 20124853, DOI: 10.1097/prs.0b013e3181c82fb0.Peer-Reviewed Original ResearchConceptsHigh-risk patientsPerfusion-related complicationsComplication rateTraditional abdominoplastyPercent of patientsPrevious abdominal surgeryAbdominal scarringActive smokingChart reviewSmoking historyAbdominal surgeryActive smokersSkin necrosisSurgical revisionWound infectionAbdominal scarRevision surgeryAbdominoplasty flapCosmetic clinicsPatientsComplicationsAbdominoplastyLipoabdominoplastySignificant differencesSurgery
2000
Long-Term Outcome of Embolotherapy and Surgery for High-Flow Extremity Arteriovenous Malformations
White R, Pollak J, Persing J, Henderson K, Thomson J, Burdge C. Long-Term Outcome of Embolotherapy and Surgery for High-Flow Extremity Arteriovenous Malformations. Journal Of Vascular And Interventional Radiology 2000, 11: 1285-1295. PMID: 11099238, DOI: 10.1016/s1051-0443(07)61302-5.Peer-Reviewed Original ResearchConceptsHigh-flow arteriovenous malformationsSuccessful embolotherapyArteriovenous malformationsExcellent long-term palliationExtremity arteriovenous malformationLong-term palliationRecurrence of symptomsLong-term efficacyMaximum painSurgical resectionSymptomatic improvementAffected handConsecutive patientsNerve blockSurgical cutdownDiffuse involvementTerm outcomesBony erosionFemoral arteryUpper extremitySkin graftsPatientsEmbolotherapy proceduresEmbolotherapyPainComplete Congenital Bony Syngnathia in a Case of Oromandibular Limb Hypogenesis Syndrome
Knoll B, Karas D, Persing J, Shin J. Complete Congenital Bony Syngnathia in a Case of Oromandibular Limb Hypogenesis Syndrome. Journal Of Craniofacial Surgery 2000, 11: 398-404. PMID: 11314391, DOI: 10.1097/00001665-200011040-00023.Peer-Reviewed Original ResearchSpontaneously Infected Cephalohematoma: Case Report and Review of the Literature
Goodwin M, Persing J, Duncan C, Shin J. Spontaneously Infected Cephalohematoma: Case Report and Review of the Literature. Journal Of Craniofacial Surgery 2000, 11: 371-375. PMID: 11314386, DOI: 10.1097/00001665-200011040-00017.Peer-Reviewed Original Research
1998
Modified Le Fort III Osteotomy in Adult Crouzon Disease
Narayan D, Persing J. Modified Le Fort III Osteotomy in Adult Crouzon Disease. Journal Of Craniofacial Surgery 1998, 9: 481-485. PMID: 9780921, DOI: 10.1097/00001665-199809000-00020.Peer-Reviewed Original Research
1994
In the Absence of Periosteum, Transplanted Fetal and Neonatal Rat Coronal Sutures Resist Osseous Obliteration
Opperman L, Persing J, Sheen R, Ogle R. In the Absence of Periosteum, Transplanted Fetal and Neonatal Rat Coronal Sutures Resist Osseous Obliteration. Journal Of Craniofacial Surgery 1994, 5: 327-332. PMID: 7833415, DOI: 10.1097/00001665-199411000-00012.Peer-Reviewed Original ResearchPrevention of “Temporal Hollowing” After Fronto-orbital Advancement for Craniosynostosis
Persing J, Mayer P, Spinelli H, Miller L, Criscuolo G. Prevention of “Temporal Hollowing” After Fronto-orbital Advancement for Craniosynostosis. Journal Of Craniofacial Surgery 1994, 5: 271-274. PMID: 7833405, DOI: 10.1097/00001665-199409000-00018.Peer-Reviewed Original Research
1993
Frontonasal dysplasia in two successive generations
Fryburg J, Persing J, Lin K. Frontonasal dysplasia in two successive generations. American Journal Of Medical Genetics 1993, 46: 712-714. PMID: 8362915, DOI: 10.1002/ajmg.1320460623.Peer-Reviewed Original ResearchCalvartal Deformity Regeneration Following Subtotal Craniectomy for Craniosynostosis
Drake D, Persing J, Berman D, Ogle R. Calvartal Deformity Regeneration Following Subtotal Craniectomy for Craniosynostosis. Journal Of Craniofacial Surgery 1993, 4: 85-89. PMID: 8324088, DOI: 10.1097/00001665-199304000-00006.Peer-Reviewed Original ResearchMalignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases
Wanebo J, Malik J, Vandenberg S, Wanebo H, Driesen N, Persing J. Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases. Cancer 1993, 71: 1247-1253. PMID: 8435801, DOI: 10.1002/1097-0142(19930215)71:4<1247::aid-cncr2820710413>3.0.co;2-s.Peer-Reviewed Original ResearchConceptsMalignant peripheral nerve sheath tumorDisease-free survivalSurgical marginsTumor sizeTumor locationSurvival timeMedian disease-free survival timeBetter disease-free survivalMedian overall survival timePeripheral nerve sheath tumorsDisease-free survival timeVirginia Health Sciences CenterAdjuvant radiation therapyExtent of surgeryWide surgical marginsNerve sheath tumorsOverall survival timeQuality of marginsNeurofibromatosis type 1Type of treatmentHealth Sciences CenterAggressive surgeryClinicopathologic studyOverall survivalPatient age
1992
The Serratus Anterior Free Tissue Transfer for Craniofacial Reconstruction
Angel M, Bridges R, Levine P, Cantrell R, Persing J. The Serratus Anterior Free Tissue Transfer for Craniofacial Reconstruction. Journal Of Craniofacial Surgery 1992, 3: 207-212. PMID: 1298423, DOI: 10.1097/00001665-199212000-00006.Peer-Reviewed Original ResearchNeurological Deterioration after Lumbar Cerebrospinal Fluid Drainage
Francel P, Persing J, Cantrell R, Levine P, Newman S. Neurological Deterioration after Lumbar Cerebrospinal Fluid Drainage. Journal Of Craniofacial Surgery 1992, 3: 145-148. PMID: 1298413, DOI: 10.1097/00001665-199211000-00006.Peer-Reviewed Original ResearchConceptsCerebrospinal fluid drainageCSF drainageFluid drainageLumbar drainageLumbar cerebrospinal fluid drainageNerve root injuryNormal neurological statusSpinal fluid drainageDrainage of CSFCerebral herniationLumbar drainage systemPersistent CSFRetraction damageNeurological statusNeurological deteriorationIntraoperative managementSerious complicationsTumor resectionPotential complicationsComa stateSylvian fissureCribriform plateRoot injurySuprachiasmatic cisternIntracranial compartment
1991
Duraplasty in Cranial Base Resection
Shaffrey M, Persing J, Shaffrey C, Jane J. Duraplasty in Cranial Base Resection. Journal Of Craniofacial Surgery 1991, 2: 152-155. PMID: 1814496, DOI: 10.1097/00001665-199112000-00008.Peer-Reviewed Original ResearchConceptsAdvanced patient ageCerebrospinal fluid leakageCranial base surgeonsCranial base resectionMiddle meningeal arteryCranial base surgeryPatient agePrimary closureTumor resectionMeningeal arteryBlood supplyDural flapRadiation therapyReconstructive optionsPrevious irradiationDural woundFluid leakageResectionDonor siteCranial baseMorbidityComplicationsDuraplastySurgeryArtery