2017
De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis
Timberlake AT, Furey CG, Choi J, Nelson-Williams C, Loring E, Galm A, Kahle K, Steinbacher D, Larysz D, Persing J, Lifton R, Bilguvar K, Mane S, Tikhonova I, Castaldi C, Knight J. De novo mutations in inhibitors of Wnt, BMP, and Ras/ERK signaling pathways in non-syndromic midline craniosynostosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: e7341-e7347. PMID: 28808027, PMCID: PMC5584457, DOI: 10.1073/pnas.1709255114.Peer-Reviewed Original ResearchConceptsBone morphogenetic proteinRas/ERKDe novo mutationsNovo mutationsRas/ERK pathwayDamaging de novo mutationsHigh locus heterogeneityRare syndromic diseaseCommon risk variantsInhibitor of WntSyndromic craniosynostosesNew genesParent-offspring triosSyndromic diseaseMorphogenetic proteinsNegative regulatorERK pathwayMore cranial suturesGenesMidline craniosynostosisRisk variantsWntLocus heterogeneityMutationsExome sequencing
1995
Repair of critical size rat calvarial defects using extracellular matrix protein gels.
Sweeney T, Opperman L, Persing J, Ogle R. Repair of critical size rat calvarial defects using extracellular matrix protein gels. Journal Of Neurosurgery 1995, 83: 710-5. PMID: 7545744, DOI: 10.3171/jns.1995.83.4.0710.Peer-Reviewed Original Research
1994
In the Absence of Periosteum, Transplanted Fetal and Neonatal Rat Coronal Sutures Resist Osseous Obliteration
Opperman L, Persing J, Sheen R, Ogle R. In the Absence of Periosteum, Transplanted Fetal and Neonatal Rat Coronal Sutures Resist Osseous Obliteration. Journal Of Craniofacial Surgery 1994, 5: 327-332. PMID: 7833415, DOI: 10.1097/00001665-199411000-00012.Peer-Reviewed Original Research
1993
Calvartal Deformity Regeneration Following Subtotal Craniectomy for Craniosynostosis
Drake D, Persing J, Berman D, Ogle R. Calvartal Deformity Regeneration Following Subtotal Craniectomy for Craniosynostosis. Journal Of Craniofacial Surgery 1993, 4: 85-89. PMID: 8324088, DOI: 10.1097/00001665-199304000-00006.Peer-Reviewed Original Research