2024
The Most Socially Vulnerable Patients Benefit the Most Following Gender Affirming Facial Surgery
Parikh N, Hu K, Ihnat J, Allam O, Diatta F, Rancu A, Wood S, Flores Perez P, Persing J, Alperovich M. The Most Socially Vulnerable Patients Benefit the Most Following Gender Affirming Facial Surgery. Journal Of Craniofacial Surgery 2024 DOI: 10.1097/scs.0000000000010718.Peer-Reviewed Original ResearchArea deprivation index scoreDeprivation index scoreSocial vulnerability index scoresSocial Vulnerability IndexMinor themesImpact of social vulnerabilityNeighborhood socioeconomic disadvantageIndex scorePatient-reported outcomesAppearance satisfactionSocioeconomic disadvantageHome addressFACE-Q modulesSocial vulnerabilityVulnerable patientsLinear regression analysisImpact of surgeryUnivariate linear regression analysisPatient benefitThemesGeo-codedLack of informationRegression analysisScoresTransportation themeFACE-Q Satisfaction Ratings Are Higher After Facial Feminization Surgery Than Hormone Replacement Therapy Alone
Almeida M, Long A, Junn A, Rivera J, Hauc S, Alper D, Glahn J, Williams M, Persing J, Alperovich M. FACE-Q Satisfaction Ratings Are Higher After Facial Feminization Surgery Than Hormone Replacement Therapy Alone. Transgender Health 2024, 9: 436-443. PMID: 39449796, PMCID: PMC11496891, DOI: 10.1089/trgh.2022.0209.Peer-Reviewed Original ResearchUsing the SCAR-Q to Evaluate Morbidity of Scars in Craniosynostosis Repair.
Parikh N, Hu K, Allam O, Lewis K, Ihnat J, Rancu A, Boroumand S, Persing J, Alperovich M. Using the SCAR-Q to Evaluate Morbidity of Scars in Craniosynostosis Repair. The Cleft Palate-Craniofacial Journal 2024, 10556656241272473. PMID: 39140877, DOI: 10.1177/10556656241272473.Peer-Reviewed Original ResearchSCAR-QCraniosynostosis surgeryPsychosocial impactPatient aesthetic satisfactionScar-related symptomsTime of surgeryType of surgeryPost-operative scarringPatients aged 8Higher patient dissatisfactionSurvey completionMann-Whitney UCraniosynostosis repairScar burdenSuture involvementEvaluate morbidityFemale patientsPearson correlation testScar appearanceMean agePatient characteristicsSurgeryCraniofacial conditionsMann-WhitneyPatientsQuantitative Assessment of Forehead Morphology Following Facial Feminization Surgery
Parikh N, Hu K, Ihnat J, Almeida M, Williams M, Alper D, Allam O, Aral A, Persing J, Alperovich M. Quantitative Assessment of Forehead Morphology Following Facial Feminization Surgery. Transgender Health 2024 DOI: 10.1089/trgh.2024.0019.Peer-Reviewed Original ResearchFacial feminization surgeryFrontonasal angleFACE-QComputerized tomographyFeminization surgeryPreoperative to postoperative changeTime of surgeryIntraclass coefficientFACE-Q modulesGender-affirming surgeryPatient-reported outcome measuresForehead contourPostoperative changesAcademic medical centerForehead morphologySurgeryPatientsQuality of lifeInclusion criteriaCT imagesMedical CenterPatient satisfactionOutcome measuresInter-rater reliabilityForeheadEvolution of Virtual Surgical Planning Use Among Craniofacial Surgeons
Moscarelli J, Hu K, Alper D, Rancu A, Salib A, Ihnat J, Parikh N, Persing J, Alperovich M. Evolution of Virtual Surgical Planning Use Among Craniofacial Surgeons. Journal Of Craniofacial Surgery 2024, 35: 1612-1615. PMID: 38949496, DOI: 10.1097/scs.0000000000010429.Peer-Reviewed Original ResearchVirtual surgical planningAmerican Society of Maxillofacial SurgeonsCraniofacial surgeonsImprove esthetic outcomesRespondents' current practiceShorter operating timeCraniofacial surgery fellowshipPlastic surgery trainingPostablative reconstructionOrthognathic surgeryEsthetic outcomeMaxillofacial surgeonsCraniofacial surgerySurgeon demographicsProcedure typeSurgical planningOperative timeSurgeon's practiceFellowship trainingFacial feminizationSurgeonsSurgery trainingSurgeryContinuous variablesSurgical trainingAXIN1 mutations in nonsyndromic craniosynostosis.
Timberlake A, Hemal K, Gustafson J, Hao L, Valenzuela I, Slavotinek A, Cunningham M, Kahle K, Lifton R, Persing J. AXIN1 mutations in nonsyndromic craniosynostosis. Journal Of Neurosurgery Pediatrics 2024, 34: 246-251. PMID: 38905707, PMCID: PMC11200303, DOI: 10.3171/2024.5.peds24115.Peer-Reviewed Original ResearchSequence dataAXIN1 mutationsCase-parent triosGenome-wide significanceCS casesNonsyndromic CSGenome sequencing projectsWnt signalingExome sequencing dataRNA sequencing dataPhenotypes associated with mutationsSequencing projectsGenetic testingInhibitor of Wnt signalingLive birthsNonsyndromic casesGenetic etiologyGenetic causeCS patientsAXIN1Nonsyndromic craniosynostosisMutationsHealthy controlsBirth defectsExomeRadiographic severity is associated with worse executive function in metopic craniosynostosis
Almeida M, Alper D, Barrero C, Parikh N, Hauc S, Moscarelli J, Golinko M, Persing J, Swanson J, Alperovich M. Radiographic severity is associated with worse executive function in metopic craniosynostosis. Child's Nervous System 2024, 1-12. PMID: 38904768, DOI: 10.1007/s00381-024-06493-7.Peer-Reviewed Original ResearchSeverity of metopic synostosisExecutive functionConners-3Neurocognitive testsBehavior Rating Inventory of Executive Function-2Endocranial bifrontal angleAssociated with worse executive functionSocial Responsiveness Scale-2Behavior Rating InventoryImpact executive functioningWorse executive functionChild Behavior ChecklistMetopic synostosisBRIEF-2Behavior ChecklistSchool ageBehavioral assessmentBehavioral difficultiesScale-2Subscale scoresAssociated with worse scoresBehavioral outcomesPhenotypic severitySociodemographic riskPre-operative CT imagesThe role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis.
Alper D, Almeida M, Hu K, Yang J, Timberlake A, Shah J, Persing J, Alperovich M. The role of genetics on behavioral outcomes in nonsyndromic sagittal synostosis. Journal Of Neurosurgery Pediatrics 2024, 34: 234-245. PMID: 38875721, DOI: 10.3171/2024.4.peds23510.Peer-Reviewed Original ResearchBehavioral outcomesNonsyndromic sagittal synostosisSocial Responsiveness Scale-2nd editionBehavior Rating InventoryAttention-deficit/hyperactivity disorderSagittal synostosisPly geneRelative to controlsExecutive functionAttention-deficit/hyperactivityExternalizing behaviorsExternalizing problemsLoss of functionBehavior problemsASD domainAssociated with worse scoresOutcomes of patientsRule-breakingParents of children aged 6Treating sagittal synostosisOlder ageAssociation of mutationsBehavior scoresSociodemographic factorsPly groupsD125. A Diffusion Tensor Imaging Comparison of White Matter Development in Nonsyndromic Craniosynostosis to Neurotypical Infants
Moscarelli J, Almeida M, Lacadie C, Hu K, Ihnat J, Parikh N, Persing J, Alperovich M. D125. A Diffusion Tensor Imaging Comparison of White Matter Development in Nonsyndromic Craniosynostosis to Neurotypical Infants. Plastic & Reconstructive Surgery Global Open 2024, 12: 127-127. PMCID: PMC11340512, DOI: 10.1097/01.gox.0001018968.87118.ff.Peer-Reviewed Original ResearchComparison of emotional and behavioral regulation between metopic and sagittal synostosis
Almeida M, Alper D, Parikh N, De Baun H, Kammien A, Persing J, Alperovich M. Comparison of emotional and behavioral regulation between metopic and sagittal synostosis. Child's Nervous System 2024, 40: 2789-2799. PMID: 38691155, DOI: 10.1007/s00381-024-06387-8.Peer-Reviewed Original ResearchIntelligence quotientBehavior Rating Inventory of Executive Function-2Wechsler Abbreviated Scale of IntelligenceSocial Responsiveness Scale-2Behavior Rating InventoryWechsler Abbreviated ScaleExecutive function subscalesChild Behavior ChecklistExecutive function scoresScale of IntelligenceWASI-IIBRIEF-2Conners-3Executive functionExternalizing behaviorsBehavior ChecklistBehavioral regulationProblems subscaleSchool ageBehavioral assessmentBehavioral difficultiesScale-2Behavioral outcomesRule-breakingBehavioral differences54. A Diffusion Tensor Imaging Comparison Of White Matter Development In Nonsyndromic Craniosynostosis To Neurotypical Infants
Moscarelli J, Almeida M, Lacadie C, Hu K, Ihnat J, Parikh N, Persing J, Alperovich M. 54. A Diffusion Tensor Imaging Comparison Of White Matter Development In Nonsyndromic Craniosynostosis To Neurotypical Infants. Plastic & Reconstructive Surgery Global Open 2024, 12: 38-38. PMCID: PMC11041127, DOI: 10.1097/01.gox.0001015308.49191.ae.Peer-Reviewed Original ResearchSports participation after craniosynostosis repair: the critical role of post-operative guidance in parental decision-making
Parikh N, Hu K, Allam O, Ihnat J, Rancu A, Boroumand S, Persing J, Alperovich M. Sports participation after craniosynostosis repair: the critical role of post-operative guidance in parental decision-making. Child's Nervous System 2024, 40: 2551-2556. PMID: 38578479, DOI: 10.1007/s00381-024-06381-0.Peer-Reviewed Original ResearchParental decision-makingContact sportsHealthcare providersSports participationMethodsParents of childrenMean comfort levelPrimary surgeonChildren aged 6American Academy of PediatricsPatient safetyAcademy of PediatricsHealthcare professionalsLimited-contactDecision-making processPearson correlation testAged 6Parental anxietyHealthcareLikert scaleChildren's participationSport involvementAmerican AcademyCraniosynostosis repairDecision-makingChi-squareA diffusion tensor imaging comparison of white matter development in nonsyndromic craniosynostosis to neurotypical infants
Moscarelli J, Almeida M, Lacadie C, Hu K, Ihnat J, Parikh N, Persing J, Alperovich M. A diffusion tensor imaging comparison of white matter development in nonsyndromic craniosynostosis to neurotypical infants. Child's Nervous System 2024, 40: 1477-1487. PMID: 38175271, DOI: 10.1007/s00381-023-06262-y.Peer-Reviewed Original Research
2023
Technique for Cephalometric Analysis of the Craniofacial Skeleton Following Facial Feminization Surgery
Williams M, Almeida M, Alper D, Allam O, Shah J, Craver A, Judge A, Rivera J, Persing J, Alperovich M. Technique for Cephalometric Analysis of the Craniofacial Skeleton Following Facial Feminization Surgery. Journal Of Craniofacial Surgery 2023, 35: 646-648. PMID: 37955450, DOI: 10.1097/scs.0000000000009885.Peer-Reviewed Original ResearchQuantifying Facial Feminization Surgery’s Impact: Focus on Patient Facial Satisfaction
Alper D, Almeida M, Hu K, De Baun H, Hosseini H, Williams M, Salib A, Shah J, Persing J, Alperovich M. Quantifying Facial Feminization Surgery’s Impact: Focus on Patient Facial Satisfaction. Plastic & Reconstructive Surgery Global Open 2023, 11: e5366. PMID: 37928639, PMCID: PMC10624460, DOI: 10.1097/gox.0000000000005366.Peer-Reviewed Original ResearchComparison of Emotional and Behavioral Regulation Between Metopic and Sagittal Synostosis
Almeida M, Alper D, Parikh N, Debaum H, Kammien A, Persing J, Alperovich M. Comparison of Emotional and Behavioral Regulation Between Metopic and Sagittal Synostosis. 2023 DOI: 10.21203/rs.3.rs-3423777/v1.Peer-Reviewed Original ResearchSocial Responsiveness Scale-2More difficultyBehavior Rating InventorySchool ageWechsler Abbreviated ScaleExecutive function scoresExecutive function subscalesExecutive Function-2Child Behavior ChecklistIntelligence quotient (IQ) testingBRIEF-2Executive functionRating InventoryAbbreviated ScaleConners 3Behavioral difficultiesBehavioral regulationProblems subscaleBehavior ChecklistBehavioral outcomesScale-2Behavioral assessmentMore childrenOverall difficultyBehavioral differencesGenerative Pre-Trained Transformers (GPT) Artificial intelligence – Assessing the Accuracy of ChatGPT as an Adjunct for Peri-operative Care
Allam O, Williams M, Almeida M, Alper D, Craver A, Persing J, Alperovich M. Generative Pre-Trained Transformers (GPT) Artificial intelligence – Assessing the Accuracy of ChatGPT as an Adjunct for Peri-operative Care. Plastic & Reconstructive Surgery Global Open 2023, 11: 132-133. PMCID: PMC10567027, DOI: 10.1097/01.gox.0000992588.09873.87.Peer-Reviewed Original ResearchTranexamic Acid in Facial Feminization Surgery: Quantifying a High-risk Setting With Exogenous Estrogen Supplementation
Alper D, Almeida M, Rivera J, Hosseini H, Williams M, Long A, Prassinos A, Mookerjee V, Persing J, Alperovich M. Tranexamic Acid in Facial Feminization Surgery: Quantifying a High-risk Setting With Exogenous Estrogen Supplementation. Journal Of Craniofacial Surgery 2023, 34: 1452-1455. PMID: 37277900, DOI: 10.1097/scs.0000000000009415.Peer-Reviewed Original ResearchConceptsVenous thromboembolic eventsSafety of TXAExogenous estrogen supplementationTranexamic acidEstrogen supplementationFacial feminization surgeryCaprini scoreVTE ratesBlood lossOperative timeFeminization surgeryHigh-risk patient populationIntraoperative tranexamic acidRisk patient populationHigh-risk settingsUnpaired t-testEstrogen therapyThromboembolic eventsRetrospective reviewHematoma rateProthrombotic agentsPatient populationProcedure typeMedical CenterElevated riskQuality and Readability of Accessible Facial Feminization Literature
Alper D, Almeida M, De Baun H, Glahn J, Rivera J, Williams M, Collar J, Mookerjee V, Persing J, Alperovich M. Quality and Readability of Accessible Facial Feminization Literature. Annals Of Plastic Surgery 2023, 90: 533-537. PMID: 37311308, DOI: 10.1097/sap.0000000000003569.Peer-Reviewed Original Research1. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia
Timberlake A, Quiat D, Cunningham M, Persing J, Luquetti D, Heike C, Seidman J, Seidman C. 1. Mutations in FOXI3 Cause Microtia and Craniofacial Microsomia. Plastic & Reconstructive Surgery Global Open 2023, 11: 1-1. PMCID: PMC10194625, DOI: 10.1097/01.gox.0000937600.62921.32.Peer-Reviewed Original Research