2014
Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
Boras-Granic K, Dann P, Wysolmerski JJ. Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland. Breast Cancer Research 2014, 16: 487. PMID: 25467960, PMCID: PMC4308878, DOI: 10.1186/s13058-014-0487-6.Peer-Reviewed Original ResearchConceptsAdult mammary glandMammary glandLabel-retaining cellsCell populationsFuture breast cancer riskStem cellsDNA label retentionBreast cancer riskStem cell populationEdU-labeled cellsEmbryonic day 18.5Label retaining cellsAdult mouse mammary glandStem/progenitor cellsMammary stem cellsStem/progenitor cell populationsSecondary mammospheresEmbryonic day 14.5Fetal exposureMouse mammary glandOvarian hormonesQuiescent stem cell populationMulti-potent stem cellsCancer riskBasal markers
2010
Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis
Coletta RD, McCoy EL, Burns V, Kawakami K, McManaman JL, Wysolmerski JJ, Ford HL. Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis. BMC Developmental Biology 2010, 10: 4. PMID: 20074369, PMCID: PMC2823684, DOI: 10.1186/1471-213x-10-4.Peer-Reviewed Original ResearchConceptsNormal mammary gland developmentAdult mammary glandMammary gland developmentMammary glandMammary developmentBreast cancerMouse modelBreast tumorigenesisEmbryonic mammary glandPostnatal mammary developmentRag1-/- miceNormal mammary gland morphogenesisGland developmentTransgenic mouse modelBreast cancer initiationViable therapeutic targetIndependent mouse modelsAdult mouse mammary glandAnti-cancer therapyMammary stem cellsFamily membersMouse mammary glandUnwanted side effectsRole of Six1Invasive carcinoma