2020
Calcium metabolism and breast cancer: Echoes of lactation?
Grinman D, Athonvarungkul D, Wysolmerski J, Jeong J. Calcium metabolism and breast cancer: Echoes of lactation? Current Opinion In Endocrine And Metabolic Research 2020, 15: 63-70. PMID: 33299957, PMCID: PMC7720883, DOI: 10.1016/j.coemr.2020.11.006.BooksBreast cancerSystemic calcium homeostasisBreast cancer cellsMaternal calciumMammary epithelial cellsCalcium metabolismBone metabolismSystemic metabolismIntracellular calciumMalignant behaviorCalcium homeostasisCalcium receptorCalcium secretionSeries of adaptationsUptake of calciumMammary glandEpithelial cellsCalcium transportCancer cellsCell proliferationExtracellular fluidCancerCalciumMetabolismLactation
2001
Temporally regulated overexpression of parathyroid hormone-related protein in the mammary gland reveals distinct fetal and pubertal phenotypes
Dunbar ME, Dann P, Brown CW, Van Houton J, Dreyer B, Philbrick WP, Wysolmerski JJ. Temporally regulated overexpression of parathyroid hormone-related protein in the mammary gland reveals distinct fetal and pubertal phenotypes. Journal Of Endocrinology 2001, 171: 403-416. PMID: 11739006, DOI: 10.1677/joe.0.1710403.Peer-Reviewed Original ResearchConceptsParathyroid hormone-related proteinHormone-related proteinPTHrP overexpressionMammary glandLobuloalveolar developmentDuctal elongationMammary developmentOverexpression of PTHrPDouble transgenic miceTransgenic mice resultsTerminal end budsEpithelial cell apoptosisPubertal phenotypesDuctal branchingEmbryonic mammary developmentTransgenic miceMice resultsPTHrPEnd budsDecrease apoptosisCell apoptosisBasal rateDuctal morphogenesisCell proliferationDuctal tree