Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.
Pober JS, Lapierre LA, Stolpen AH, Brock TA, Springer TA, Fiers W, Bevilacqua MP, Mendrick DL, Gimbrone MA. Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species. The Journal Of Immunology 1987, 138: 3319-24. PMID: 3494766, DOI: 10.4049/jimmunol.138.10.3319.Peer-Reviewed Original ResearchConceptsTumor necrosis factorAction of lymphotoxinCultured human endothelial cellsHuman endothelial cellsIL-1 speciesPhorbol ester pretreatmentNecrosis factorLeukocyte adhesionEndothelial cellsRecombinant human tumor necrosis factorSecretion of lymphotoxinExpression of HLAIL-1 betaIL-1 alphaInhibited inductionHuman tumor necrosis factorActivated T cellsPhorbol esterInflammatory leukocyte adhesionRecombinant human lymphotoxinInflammatory cellsT cellsIL-1Hr pretreatmentIFN-gammaEffects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells
Pober J. Effects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells. Novartis Foundation Symposia 1987, 131: 170-191. PMID: 3330009, DOI: 10.1002/9780470513521.ch12.Peer-Reviewed Original ResearchConceptsIL-1 betaHuman endothelial cellsIL-1 alphaRelated cytokinesVascular endothelial cellsEndothelial cellsNecrosis factorEndothelial leucocyte adhesion moleculeIntercellular adhesion molecule-1Tumor necrosis factorInterleukin-1 betaAdhesion molecule-1Endothelial cell activationInterleukin-1 alphaCultured human endothelial cellsPhorbol esterEffects of TNFRecombinant human TNFCytoplasmic calcium concentrationIL-1 speciesMechanism of actionHEC adhesivenessInflammatory leucocytesCell surface expressionProtein kinase C pathway