1991
Expression of endothelial-leukocyte adhesion molecule-1 in elicited late phase allergic reactions.
Leung DY, Pober JS, Cotran RS. Expression of endothelial-leukocyte adhesion molecule-1 in elicited late phase allergic reactions. Journal Of Clinical Investigation 1991, 87: 1805-1809. PMID: 1708785, PMCID: PMC295299, DOI: 10.1172/jci115201.Peer-Reviewed Original ResearchConceptsLate-phase reactionInflammatory cellsAllergic reactionsEC activationLate-phase allergic reactionsEndothelial leukocyte adhesion molecule-1Adhesion moleculesIntradermal allergen injectionSequential skin biopsiesInflammatory cell infiltrateNeutrophil adhesion moleculesEndothelial leukocyte adhesion moleculeAllergic skin reactionsELAM-1 expressionOrgan cultureAdhesion molecule-1Skin organ cultureAtopic patientsCell infiltrateEndothelial activationAllergen injectionRespiratory allergySkin reactionsTNF-alphaIntradermal injection
1987
Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture.
Messadi DV, Pober JS, Fiers W, Gimbrone MA, Murphy GF. Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture. The Journal Of Immunology 1987, 139: 1557-62. PMID: 3497975, DOI: 10.4049/jimmunol.139.5.1557.Peer-Reviewed Original ResearchConceptsTumor necrosis factorActivation antigensNecrosis factorInterleukin-1Microvascular endotheliumEndothelial cellsEndothelial activation antigenMediators interleukin-1Postcapillary venular endotheliumCultured human umbilical vein endothelial cellsSuperficial vascular plexusOrgan cultureHuman skin organ cultureShort-term organ cultureHuman umbilical vein endothelial cellsSkin organ cultureUmbilical vein endothelial cellsVenular endothelial cellsMicrovascular stainingPostcapillary venular endothelial cellsVein endothelial cellsEndogenous cytokinesLymphocyte traffickingInterleukin-2Venular endothelium