2020
Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium
Lysyy T, Bracaglia LG, Qin L, Albert C, Pober JS, Tellides G, Saltzman WM, Tietjen GT. Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium. Bioengineering & Translational Medicine 2020, 5: e10154. PMID: 32440561, PMCID: PMC7237142, DOI: 10.1002/btm2.10154.Peer-Reviewed Original ResearchVessel perfusion systemAnimal modelsPerfusion systemProcess of inflammationVessel segmentsSame human donorEffective clinical translationImmunodeficient miceUmbilical cordRodent modelsHuman donorsEndothelial cellsHuman vesselsBiologic relevanceBiologic replicatesClinical translationSubsequent studiesEfficacyCultured cellsModular chambersCell culturesVivoCellsQuantitative assayVessels
2008
Human hepatic stellate cells and hepatocyte co‐cultures maintain differentiation in vitro and in vivo
Harding M, Barnaeva E, Bustamante M, Lepus C, Rahner C, Pober J, Sjogren M, Rojkind M. Human hepatic stellate cells and hepatocyte co‐cultures maintain differentiation in vitro and in vivo. The FASEB Journal 2008, 22: 465.3-465.3. DOI: 10.1096/fasebj.22.1_supplement.465.3.Peer-Reviewed Original ResearchHepatic stellate cellsStellate cellsChronic drug toxicityHuman hepatic stellate cellsSCID/bg miceLong-term toxicityBile duct-like structuresDuct-like structuresHepatitis infectionCK19 mRNAMature human hepatocytesBg miceLiver pathogensAbdominal wallDrug toxicityExpression of albuminLiver repopulationNewborn subjectsΑ-fetoproteinEpithelial cellsHuman hepatocytesΑ1-antitrypsinLong-term cultureSca-1Vivo
1978
Phosphorylation in vivo and in vitro of human histocompatibility antigens (HLA-A and HLA-B) in the carboxy-terminal intracellular domain.
Pober JS, Guild BC, Strominger JL. Phosphorylation in vivo and in vitro of human histocompatibility antigens (HLA-A and HLA-B) in the carboxy-terminal intracellular domain. Proceedings Of The National Academy Of Sciences Of The United States Of America 1978, 75: 6002-6006. PMID: 282620, PMCID: PMC393105, DOI: 10.1073/pnas.75.12.6002.Peer-Reviewed Original Research