2022
Assembly and architecture of the type III secretion sorting platform
Soto J, Galán J, Lara-Tejero M. Assembly and architecture of the type III secretion sorting platform. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2218010119. PMID: 36512499, PMCID: PMC9907115, DOI: 10.1073/pnas.2218010119.Peer-Reviewed Original ResearchConceptsType III secretion machinesType III secretion systemTarget eukaryotic cellsType III secretionSecretion of proteinsBacterial nanomachinesSecretion machineEukaryotic cellsExport pathwayImportant bacterial pathogensSecretion systemBacterial structureAntivirulence strategiesCoordinated mechanismFunctional complexityBacterial pathogensGenetic deletionStructure modelingProtein deliveryAssemblyRational developmentCross-linking strategyAssembly processProteinDeletion
2001
CdtA, CdtB, and CdtC Form a Tripartite Complex That Is Required for Cytolethal Distending Toxin Activity
Lara-Tejero M, Galán J. CdtA, CdtB, and CdtC Form a Tripartite Complex That Is Required for Cytolethal Distending Toxin Activity. Infection And Immunity 2001, 69: 4358-4365. PMID: 11401974, PMCID: PMC98507, DOI: 10.1128/iai.69.7.4358-4365.2001.Peer-Reviewed Original ResearchConceptsCytolethal distending toxinTriggers cell cycle arrestActive subunitCell cycle arrestImportant bacterial pathogensTripartite complexCell cycleCDT holotoxinDistending toxinCycle arrestCDT activityCellular toxicityCdtCSubunitsBacterial pathogensRelated toxinsCdtBToxin activityB chainB subunitCdtC.Toxic activityTripartite toxinCampylobacter jejuniTarget cells