2001
Salmonella entry into host cells: the work in concert of type III secreted effector proteins
Zhou D, Galán J. Salmonella entry into host cells: the work in concert of type III secreted effector proteins. Microbes And Infection 2001, 3: 1293-1298. PMID: 11755417, DOI: 10.1016/s1286-4579(01)01489-7.Peer-Reviewed Original ResearchConceptsActin cytoskeleton rearrangementCytoskeleton rearrangementActin dynamicsHost cellsHost actin dynamicsHost signal transductionType III secretion systemActin-binding proteinsSPI-1 type III secretion systemEffector proteinsSecretion systemSignal transductionActin rearrangementBacterial proteinsSalmonella entryIntestinal epithelial cellsBacterial uptakeCdc42Coordinated stepsProteinEpithelial cellsRacRearrangementCellsTransduction
1993
Signal transduction and invasion of epithelial cells by S. typhimurium
Pace J, Hayman M, Galán J. Signal transduction and invasion of epithelial cells by S. typhimurium. Cell 1993, 72: 505-514. PMID: 8382566, DOI: 10.1016/0092-8674(93)90070-7.Peer-Reviewed Original ResearchMeSH KeywordsArachidonate 5-LipoxygenaseArachidonic AcidCalciumCalcium-Calmodulin-Dependent Protein KinasesCells, CulturedEndocytosisEpidermal Growth FactorEpitheliumErbB ReceptorsPhospholipases APhospholipases A2PhosphorylationProtein KinasesSalmonella InfectionsSalmonella typhimuriumSignal TransductionSRS-AConceptsCultured epithelial cellsBacterial entryMitogen-activated protein kinaseEpithelial cellsS. typhimurium invasionS. typhimuriumEpidermal growth factor receptorSignal transductionProtein kinaseGrowth factor receptorHenle-407 cellsTyphimurium invasionHost cellsPathogenicity of SalmonellaFactor receptorInfected cellsMutantsInvasionCalcium fluxCellsPhospholipase A2TyphimuriumIntracellular calciumActivationFree intracellular calcium
1992
Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium
Galán J, Pace J, Hayman M. Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium. Nature 1992, 357: 588-589. PMID: 1608468, DOI: 10.1038/357588a0.Peer-Reviewed Original ResearchConceptsHenle-407 cellsEpidermal growth factor receptorMammalian cellsGrowth factor receptorTyrosine phosphorylationCultured mammalian cellsProtein tyrosine phosphorylationFactor receptorInternalization of SalmonellaCell surface receptorsCultured epithelial cellsAddition of EGFSuch phosphorylationSignal transductionSalmonella genesSalmonella typhimuriumEGF receptorS. typhimuriumIsogenic strainsEscherichia coliPhosphorylationEpithelial cellsGenesInternalizationInvasion