1993
Prognostic significance of K-ras mutations in colorectal carcinoma
Benhattar J, Losi L, Chaubert P, Givel J, Costa J. Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 1993, 104: 1044-1048. PMID: 8462792, DOI: 10.1016/0016-5085(93)90272-e.Peer-Reviewed Original ResearchConceptsK-ras mutationsPrognostic significanceColorectal carcinomaK-ras geneRecurrent diseaseCodon 12Good prognostic factorAdvanced colorectal carcinomaPossible prognostic significanceHuman colorectal carcinomaPolymerase chain reaction-based techniquesDukes' BPrognostic factorsColorectal cancerPrimary tumorOverall prevalenceHigh riskPatientsRas mutationsCarcinomaHuman tumorsTumorsDiseasePrevalenceGGT
1986
High‐grade soft tissue sarcomas of the extremities
Potter D, Kinsella T, Glatstein E, Wesley R, White D, Seipp C, Chang A, Lack E, Costa J, Rosenberg S. High‐grade soft tissue sarcomas of the extremities. Cancer 1986, 58: 190-205. PMID: 3518911, DOI: 10.1002/1097-0142(19860701)58:1<190::aid-cncr2820580133>3.0.co;2-5.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisAdolescentAdultAgedAmputation, SurgicalAntineoplastic Combined Chemotherapy ProtocolsArmChildClinical Trials as TopicCombined Modality TherapyFemaleFollow-Up StudiesHumansLegMaleMiddle AgedNeoplasm MetastasisNeoplasm Recurrence, LocalPrognosisRandom AllocationSarcomaThighConceptsHigh-grade soft tissue sarcomasSoft tissue sarcomasNational Cancer InstituteLimb-sparing proceduresSignificant prognostic variablesOverall survivalAdjuvant chemotherapyTissue sarcomasPrognostic variablesDecreased overall survivalOutcomes of patientsDisease-free survivalMicroscopic marginsPostoperative radiotherapyFirst recurrenceProspective trialRecurrent diseaseSurgery BranchHistologic typeLocal excisionRandomized trialsPatient refusalTumor sizeCancer InstitutePatients