2001
Detection of the Mutated K-Ras Biomarker in Colorectal Carcinoma
Doolittle B, Emanuel J, Tuttle C, Costa J. Detection of the Mutated K-Ras Biomarker in Colorectal Carcinoma. Experimental And Molecular Pathology 2001, 70: 289-301. PMID: 11418008, DOI: 10.1006/exmp.2001.2364.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorColorectal NeoplasmsDeoxyribonuclease EcoRIDNADNA, NeoplasmFecesGenes, rasHumansIndicators and ReagentsMutationPolymerase Chain ReactionPolymorphism, Single-Stranded ConformationalQuaternary Ammonium CompoundsReference ValuesReproducibility of ResultsSite-Specific DNA-Methyltransferase (Adenine-Specific)Trimethyl Ammonium CompoundsConceptsColorectal carcinomaStool samplesHealthy patientsK-rasReliable screening testDouble-blind formatK-ras mutationsWild-type K-rasK-ras oncogeneK-ras sequencesCommon malignancyCRC tumorsPolymerase chain reactionEarly lesionsStool DNANoninvasive screenScreening testTumor tissueGenetic biomarkersHuman stoolPatientsEarly detectionHigh false positive rateSingle-strand conformation polymorphismTissue DNA
1996
Highly Sensitive Nonradioactive Single-strand Conformational Polymorphism
Emanuel J, Damico C, Ahn S, Bautista D, Costa J. Highly Sensitive Nonradioactive Single-strand Conformational Polymorphism. Applied Immunohistochemistry & Molecular Morphology 1996, 5: 260-264. PMID: 8955617, DOI: 10.1097/00019606-199612000-00006.Peer-Reviewed Original ResearchPicoGreen Quantitation of DNA: Effective Evaluation of Samples Pre-or Psost-PCR
Ahn S, Costa J, Emanuel J. PicoGreen Quantitation of DNA: Effective Evaluation of Samples Pre-or Psost-PCR. Nucleic Acids Research 1996, 24: 2623-2625. PMID: 8692708, PMCID: PMC145983, DOI: 10.1093/nar/24.13.2623.Peer-Reviewed Original Research
1975
Evaluation of the lymphocyte blastogenic response by rapid flow analysis
Costa J, Cassidy M, Yee C. Evaluation of the lymphocyte blastogenic response by rapid flow analysis. Journal Of Immunological Methods 1975, 8: 339-344. PMID: 127812, DOI: 10.1016/0022-1759(75)90055-1.Peer-Reviewed Original Research