1993
Prognostic significance of K-ras mutations in colorectal carcinoma
Benhattar J, Losi L, Chaubert P, Givel J, Costa J. Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 1993, 104: 1044-1048. PMID: 8462792, DOI: 10.1016/0016-5085(93)90272-e.Peer-Reviewed Original ResearchConceptsK-ras mutationsPrognostic significanceColorectal carcinomaK-ras geneRecurrent diseaseCodon 12Good prognostic factorAdvanced colorectal carcinomaPossible prognostic significanceHuman colorectal carcinomaPolymerase chain reaction-based techniquesDukes' BPrognostic factorsColorectal cancerPrimary tumorOverall prevalenceHigh riskPatientsRas mutationsCarcinomaHuman tumorsTumorsDiseasePrevalenceGGT
1988
Interdisciplinary detection of soft tissue sarcomas. Diagnosis, grading and staging.
Leyvraz S, Costa J. Interdisciplinary detection of soft tissue sarcomas. Diagnosis, grading and staging. Die Orthopädie 1988, 17: 121-7. PMID: 3290794.Peer-Reviewed Original ResearchMeSH KeywordsHumansNeoplasm StagingPatient Care TeamReferral and ConsultationSarcomaSoft Tissue NeoplasmsConceptsSoft tissue sarcomasTissue sarcomasDifferent prognostic factorsManagement of patientsStratification of patientsPrognostic factorsSimilar prognosisSurgical marginsHistological diagnosisStaging systemClinical aspectsOptimal diagnosisTumorsPatientsDiagnosisPrognosisSarcomaStagingCliniciansPathologistsGrading
1985
Results of multimodality therapy of resectable soft-tissue sarcomas of the retroperitoneum.
Glenn J, Sindelar W, Kinsella T, Glatstein E, Tepper J, Costa J, Baker A, Sugarbaker P, Brennan M, Seipp C. Results of multimodality therapy of resectable soft-tissue sarcomas of the retroperitoneum. Surgery 1985, 97: 316-25. PMID: 3975851.Peer-Reviewed Original ResearchConceptsRandomized studyTwo-year actuarial survival ratesSurvival rateResectable soft tissue sarcomaSevere bone marrow suppressionAggressive multimodality treatmentResectable retroperitoneal sarcomasSevere radiation enteritisActuarial survival rateBone marrow suppressionCyclophosphamide-induced cystitisSoft tissue sarcomasAdjuvant chemotherapyChemotherapy armPostoperative chemotherapyRetroperitoneal sarcomaChemotherapy regimenMajor morbidityMultimodality therapyRadiation enteritisBowel resectionMarrow suppressionMultimodality treatmentMajor complicationsCardiac toxicity