2002
Regulation of T cell-dependent autoantibody production by a γδ T cell line derived from lupus-prone mice
Fujii T, Okada M, Craft J. Regulation of T cell-dependent autoantibody production by a γδ T cell line derived from lupus-prone mice. Cellular Immunology 2002, 217: 23-35. PMID: 12425998, DOI: 10.1016/s0008-8749(02)00509-9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, AntinuclearApoptosisB-LymphocytesCell LineCoculture TechniquesCytotoxicity Tests, ImmunologicDNAInterleukin-10Lupus Erythematosus, SystemicLymphocyte ActivationLymphocyte CooperationMiceMice, Inbred C57BLMice, Inbred MRL lprMice, KnockoutReceptors, Antigen, T-Cell, alpha-betaReceptors, Antigen, T-Cell, gamma-deltaT-Lymphocytes, Helper-InducerTumor Necrosis Factor-alphaConceptsGammadelta T cell linesT cell linesAnti-dsDNA productionMRL/B cellsAutoantibody productionCell linesLupus-prone miceMRL/MpGammadelta T cellsT helper cell linesB cell collaborationActivated B cellsContact-dependent mannerAlphabeta TSevere lupusGammadelta TAutoantibody synthesisMurine lupusLupus-proneT cellsCell collaborationHelper cell lineMiceLupus
1996
Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
Wen L, Pao W, Wong FS, Peng Q, Craft J, Zheng B, Kelsoe G, Dianda L, Owen MJ, Hayday AC. Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. Journal Of Experimental Medicine 1996, 183: 2271-2282. PMID: 8642336, PMCID: PMC2192585, DOI: 10.1084/jem.183.5.2271.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutoantibodiesClone CellsFlow CytometryGerminal CenterHumansImmunoglobulin Class SwitchingImmunoglobulin EImmunoglobulin GLupus Erythematosus, SystemicLymphocyte DepletionMiceMice, Inbred NODMice, Inbred StrainsMice, KnockoutMice, SCIDReceptors, Antigen, T-Cell, alpha-betaSpleenT-LymphocytesConceptsSystemic lupus erythematosusBeta T cellsAlpha/beta T cellsGamma/delta T cellsDelta T cellsT cell helpT cellsT cell receptorCell helpT cell-mediated conditionsHuman systemic lupus erythematosusSevere combined immunodeficient (SCID) miceDevelopment of autoantibodiesCombined Immunodeficient MiceT-cell immunodeficiencyClass-switched antibodiesB cell collaborationGerminal center formationLupus erythematosusAutoantibody productionLymphoid folliclesImmunoglobulin class switchingIgE synthesisAlpha/betaCell immunodeficiency