2023
T follicular helper cells in cancer, tertiary lymphoid structures, and beyond
Cui C, Craft J, Joshi N. T follicular helper cells in cancer, tertiary lymphoid structures, and beyond. Seminars In Immunology 2023, 69: 101797. PMID: 37343412, DOI: 10.1016/j.smim.2023.101797.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsTumor-associated tertiary lymphoid structuresFollicular helper cellsCD8 T cellsTertiary lymphoid structuresSecondary lymphoid organsT cellsHelper cellsLymphoid structuresImmune cellsB cellsCD4 T follicular helper cellsT Follicular Helper CellsTumor-infiltrating immune cellsCurrent immunotherapy regimensCheckpoint blockade immunotherapyCD4 T cellsImmune cell componentsLimited response rateFunctional immune cellsNovel therapeutic targetPotential therapeutic benefitT cell-B cell interactionsBlockade immunotherapyImmunotherapy regimensLymphoid organs
2015
A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control
Xin G, Schauder DM, Lainez B, Weinstein JS, Dai Z, Chen Y, Esplugues E, Wen R, Wang D, Parish IA, Zajac AJ, Craft J, Cui W. A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control. Cell Reports 2015, 13: 1118-1124. PMID: 26527008, PMCID: PMC4859432, DOI: 10.1016/j.celrep.2015.09.069.Peer-Reviewed Original ResearchConceptsCD8 T cellsChronic viral infectionsBATF expressionT cellsIL-21Chronic infectionEffector functionsViral infectionCD8 T cell effector functionsAnti-viral effector functionsCD8 T cell responsesCD8 T cell immunityT cell effector functionT cell immunityCD4 T cellsT cell responsesCell effector functionsT cell persistenceT cell maintenanceBlimp-1 expressionCD8 responsesCD4 helpCell immunityViral controlTranscription factor expression
2012
IL-10-IL-21-STAT3 axis regulates memory CD8 T cell development (110.9)
Cui W, Liu Y, Weinstein J, Craft J, Kaech S. IL-10-IL-21-STAT3 axis regulates memory CD8 T cell development (110.9). The Journal Of Immunology 2012, 188: 110.9-110.9. DOI: 10.4049/jimmunol.188.supp.110.9.Peer-Reviewed Original ResearchCD8 T cellsMemory T cellsMemory CD8 T cell developmentMemory CD8 T cellsCD8 T cell developmentT cellsT cell developmentIL-21IL-10Virus-specific CD8 T cellsBCL-6Effector CD8 T cellsProtective memory T cellsCentral memory T cellsMemory CD8 T cell differentiationCD8 T cell differentiationAcute LCMV infectionMemory precursor cellsCell developmentMemory cell developmentSTAT3-SOCS3 pathwayT cell differentiationAcute infectionLCMV infectionIL-12
2011
Expansion of IL-7Ralow memory CD8 T cells in human lupus (101.19)
Lee N, Shah K, Shin M, Kim S, Craft J, Kang I. Expansion of IL-7Ralow memory CD8 T cells in human lupus (101.19). The Journal Of Immunology 2011, 186: 101.19-101.19. DOI: 10.4049/jimmunol.186.supp.101.19.Peer-Reviewed Original ResearchSystemic lupus erythematosusDevelopment of SLESLE Disease Activity IndexMemory CD8SLE patientsT cellsCell subsetsHealthy controlsImmunopathogenesis of SLEAbstract Systemic lupus erythematosusHomeostatic cytokine IL-15IL-7 receptor alphaMemory CD8 T cellsCytotoxic molecules perforinHomeostasis of CD8Disease activity indexRole of CD8Cytokine IL-15CD8 T cellsImmune complex depositionProduction of autoantibodiesInflammatory autoimmune disorderT cell receptorDisease activityLupus erythematosus