1984
The antibody response in Lyme disease.
Craft JE, Grodzicki RL, Shrestha M, Fischer DK, García-Blanco M, Steere AC. The antibody response in Lyme disease. The Yale Journal Of Biology And Medicine 1984, 57: 561-5. PMID: 6393607, PMCID: PMC2590019.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayHumoral immune responseAntibody responseImmune responseIndirect immunofluorescenceLyme diseaseI. dammini spirocheteLyme arthritis patientsSpecific IgG responseSpecific IgM responseMonths of remissionSpecific IgM levelsIxodes dammini spirocheteLyme disease seraCross-reactive antibodiesTotal serum IgM.Lyme disease patientsAbsorption of seraArthritis patientsLyme arthritisIgG responsesIgM responseIgM levelsSpirochetal antigensDisease patients
1983
The Spirochetal Etiology of Lyme Disease
Steere A, Grodzicki R, Kornblatt A, Craft J, Barbour A, Burgdorfer W, Schmid G, Johnson E, Malawista S. The Spirochetal Etiology of Lyme Disease. New England Journal Of Medicine 1983, 308: 733-740. PMID: 6828118, DOI: 10.1056/nejm198303313081301.Peer-Reviewed Original ResearchConceptsLyme diseaseAntibody titersIgM titersSpecific IgM antibody titersSpecific IgG antibody titersElevated IgM titersI. dammini spirocheteIgG antibody titersIgM antibody titersTiters of IgGOnset of diseaseInfectious mononucleosisControl patientsImmunologic featuresIgG titersEarly diseaseControl subjectsSpirochetal etiologySkin lesionsCerebrospinal fluidPatientsLate manifestationSixth weekDiseaseTiters