2000
Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies
Nagaraju K, Raben N, Loeffler L, Parker T, Rochon P, Lee E, Danning C, Wada R, Thompson C, Bahtiyar G, Craft J, van Huijsduijnen R, Plotz P. Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 9209-9214. PMID: 10922072, PMCID: PMC16847, DOI: 10.1073/pnas.97.16.9209.Peer-Reviewed Original ResearchConceptsMHC class IMyositis-specific autoantibodiesClass IAutoimmune diseasesSkeletal muscleHuman inflammatory myopathiesHuman myositisInflammatory myopathiesAutoimmune myositisImmunological featuresSpontaneous human diseaseYoung miceAutoantibodiesMuscle cellsNonspecific eventsDiseaseMiceMyositisMuscleCommon specificityHuman diseasesSpecific patternsSpecificityStimuliMyopathy
1997
Revisiting autoantibody profiles in systemic lupus erythematosus.
Olhoffer IH, Peng SL, Craft J. Revisiting autoantibody profiles in systemic lupus erythematosus. The Journal Of Rheumatology 1997, 24: 297-302. PMID: 9034986.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusImmune dysregulationLupus erythematosusAutoantibody profileAutoimmune responseAutoantibody specificitiesU1-RNPGlobal immune dysregulationAutoantibody-positive patientsSoluble autoantigensUbiquitous autoantigensPositive patientsIndividual patientsRetrospective analysisPatientsErythematosusAutoantibodiesAutoantigensDysregulationSpecificityBroad spectrumAutoimmunityDefinitive assayPrevalence
1996
Spliceosomal snRNPs Autoantibodies
Peng S, Craft J. Spliceosomal snRNPs Autoantibodies. 1996, 774-782. DOI: 10.1016/b978-044482383-0/50119-9.Peer-Reviewed Original ResearchConnective tissue diseaseAntinuclear antibody testAnti-snRNP antibodiesTissue diseaseSystemic lupus erythematosusImmunofluorescent antinuclear antibody testAnti-Sm specificityLupus erythematosusClinical presentationRheumatological diseasesAutoantibodiesAntibody testDiseaseRNA epitopeAntibodiesSpecificityErythematosusIntensive effortsAutoantibodies to glycyl–transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity
Hirakata M, Suwa A, Takeda Y, Matsuoka Y, Irimajiri S, Targoff I, Hardin J, Craft J. Autoantibodies to glycyl–transfer RNA synthetase in myositis. Association with dermatomyositis and immunologic heterogeneity. Arthritis & Rheumatism 1996, 39: 146-151. PMID: 8546723, DOI: 10.1002/art.1780390119.Peer-Reviewed Original ResearchConceptsTRNA synthetase antibodiesImmunologic heterogeneitySynthetase antibodiesTransfer RNA synthetase antibodiesPolymyositis/dermatomyositisInterstitial lung diseaseIdentification of antibodiesRheumatic diseasesLung diseaseClinical significanceEpitope specificityPatientsAutoantibodiesImmunoblotting findingsSerumAntibodiesDiseaseDermatomyositisMyositisRNA synthetaseImmunoprecipitation assaysAssociationGlycyl-tRNA synthetaseSpecificityFindings