1998
Influence of antigen organization on the development of lupus autoantibodies
Fatenejad S, Bennett M, Moslehi J, Craft J. Influence of antigen organization on the development of lupus autoantibodies. Arthritis & Rheumatism 1998, 41: 603-612. PMID: 9550469, DOI: 10.1002/1529-0131(199804)41:4<603::aid-art7>3.0.co;2-e.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodiesAutoantibodiesAutoantigensGene ExpressionHeLa CellsHumansImmune ToleranceImmunizationLupus Erythematosus, SystemicMiceMice, Inbred C57BLMice, Inbred StrainsRecombinant Fusion ProteinsRecombinant ProteinsRibonucleoprotein, U1 Small NuclearRibonucleoproteins, Small NuclearRNA-Binding ProteinsT-LymphocytesTumor Cells, CulturedConceptsSystemic lupus erythematosusDevelopment of antibodiesH-2b backgroundDevelopment of lupusT cell responsesT cell toleranceAssessment of antibodiesNative snRNP particlesTypical immune responseLupus erythematosusAutoimmune responseNormal miceAntigen organizationImmune responseForeign immunogensH-2kCell toleranceMajor autoantigenCell responsesMiceRandom orderAntibodiesEukaryotic expression vectorLupusAutoantigens
1996
Association of RNase mitochondrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: a possible coordinate role in ribosome biogenesis.
Lee B, Matera AG, Ward DC, Craft J. Association of RNase mitochondrial RNA processing enzyme with ribonuclease P in higher ordered structures in the nucleolus: a possible coordinate role in ribosome biogenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1996, 93: 11471-11476. PMID: 8876159, PMCID: PMC38081, DOI: 10.1073/pnas.93.21.11471.Peer-Reviewed Original ResearchConceptsMitochondrial RNA processing enzymeRibosomal RNA maturationRNA processing enzymesRNA maturationRibonuclease PRNase PProcessing enzymesSitu hybridization experimentsRNA structural motifsRibosome biogenesisRibosome assemblySmall subpopulationRibonucleoprotein particleRNA componentMacromolecular complexesRNA transcriptsHybridization experimentsFractionation experimentsCoordinate roleCytoplasmic structuresAffinity selectionEnzymeStructural motifsMethyl oligoribonucleotideNucleoliAnti-U5 Small Nuclear Ribonucleoprotein (snRNP) Antibodies: A Rare Anti-U snRNP Specificity
Okano Y, Targoff I, Oddis C, Fujii T, Kuwana M, Tsuzaka K, Hirakata M, Mimori T, Craft J, Medsger T. Anti-U5 Small Nuclear Ribonucleoprotein (snRNP) Antibodies: A Rare Anti-U snRNP Specificity. Clinical Immunology 1996, 81: 41-47. PMID: 8808640, DOI: 10.1006/clin.1996.0155.Peer-Reviewed Original Research
1993
Comparison of the drosophila melanogaster, human and murine sm b cDNAs: evolutionary conservation
Brunet C, Quan T, Craft J. Comparison of the drosophila melanogaster, human and murine sm b cDNAs: evolutionary conservation. Gene 1993, 124: 269-273. PMID: 7680326, DOI: 10.1016/0378-1119(93)90404-q.Peer-Reviewed Original ResearchConceptsD. melanogaster proteinB polypeptidesConservative aa substitutionsCDNA nucleotide sequenceDeduced aa sequencesC-terminal portionEvolutionary conservationDrosophila melanogasterMouse clonesNucleotide sequenceB proteinSequence identityAa sequencesB cDNAReticulocyte lysateEvolutionary stabilityMurine cellsSpecies linesAmino acidsCDNAProtein BProteinAa substitutionsHuman anti-Sm antibodyCell lines
1991
PBC 95K, a 95‐kilodalton nuclear autoantigen in primary biliary cirrhosis
Evans J, Reuben A, Craft J. PBC 95K, a 95‐kilodalton nuclear autoantigen in primary biliary cirrhosis. Arthritis & Rheumatism 1991, 34: 731-736. PMID: 2053918, DOI: 10.1002/art.1780340614.Peer-Reviewed Original ResearchConceptsPrimary biliary cirrhosisAntinuclear antibodiesBiliary cirrhosisANA-positive samplesConnective tissue diseaseSera of patientsANA-positive seraHEp-2 cellsPBC patientsLiver diseaseTissue diseaseNuclear dotsPatientsIndirect immunofluorescenceNuclear autoantigensStaining patternAffinity-purified antibodiesSerumAntibodiesCirrhosisDiseaseAutoantigensTiters
1990
Human Ro ribonucleoprotein particles: characterization of native structure and stable association with the La polypeptide.
Boire G, Craft J. Human Ro ribonucleoprotein particles: characterization of native structure and stable association with the La polypeptide. Journal Of Clinical Investigation 1990, 85: 1182-1190. PMID: 1690756, PMCID: PMC296550, DOI: 10.1172/jci114551.Peer-Reviewed Original ResearchConceptsHY4 RNAStable associationNative structurePossible functional associationRo RNPsCultured HeLa cellsRNA componentHY5 RNAFunctional associationHeLa cellsPolypeptideLa RNPsRNARNPHuman RoDiscrete subpopulationsMacromolecular targetsPotential macromolecular targetsRelated diseasesRNPsRibonucleoproteinHY1Characteristic physicochemical propertiesStable componentHY3
1989
An immunological determinant of RNase P protein is conserved between Escherichia coli and humans.
Mamula MJ, Baer M, Craft J, Altman S. An immunological determinant of RNase P protein is conserved between Escherichia coli and humans. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 8717-8721. PMID: 2479027, PMCID: PMC298359, DOI: 10.1073/pnas.86.22.8717.Peer-Reviewed Original ResearchMolecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles.
Ohosone Y, Mimori T, Griffith A, Akizuki M, Homma M, Craft J, Hardin JA. Molecular cloning of cDNA encoding Sm autoantigen: derivation of a cDNA for a B polypeptide of the U series of small nuclear ribonucleoprotein particles. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 4249-4253. PMID: 2524838, PMCID: PMC287428, DOI: 10.1073/pnas.86.11.4249.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusSm snRNPsHuman fibroblast cDNA libraryAmino acidsAlternative splicing mechanismLupus erythematosusFibroblast cDNA librarySmall nuclear ribonucleoproteinOpen reading frameAmino acid sequenceSplicing mechanismMolecular cloningCDNA libraryNuclear ribonucleoproteinReading frameAnti-Sm antibodiesB polypeptidesAcid sequenceCOOH terminusNH2 terminusCDNAComplete homologySnRNPsPolypeptide NPolypeptide
1988
Antibodies in human serum that precipitate ribonuclease P.
Gold HA, Craft J, Hardin JA, Bartkiewicz M, Altman S. Antibodies in human serum that precipitate ribonuclease P. Proceedings Of The National Academy Of Sciences Of The United States Of America 1988, 85: 5483-5487. PMID: 2456570, PMCID: PMC281781, DOI: 10.1073/pnas.85.15.5483.Peer-Reviewed Original Research