2000
Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies
Nagaraju K, Raben N, Loeffler L, Parker T, Rochon P, Lee E, Danning C, Wada R, Thompson C, Bahtiyar G, Craft J, van Huijsduijnen R, Plotz P. Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 9209-9214. PMID: 10922072, PMCID: PMC16847, DOI: 10.1073/pnas.97.16.9209.Peer-Reviewed Original ResearchConceptsMHC class IMyositis-specific autoantibodiesClass IAutoimmune diseasesSkeletal muscleHuman inflammatory myopathiesHuman myositisInflammatory myopathiesAutoimmune myositisImmunological featuresSpontaneous human diseaseYoung miceAutoantibodiesMuscle cellsNonspecific eventsDiseaseMiceMyositisMuscleCommon specificityHuman diseasesSpecific patternsSpecificityStimuliMyopathy
1992
Autoantibodies to small nuclear and cytoplasmic ribonucleoproteins in japanese patients with inflammatory muscle disease
Hirakata M, Mimori T, Akizuki M, Craft J, Hardin J, Homma M. Autoantibodies to small nuclear and cytoplasmic ribonucleoproteins in japanese patients with inflammatory muscle disease. Arthritis & Rheumatism 1992, 35: 449-456. PMID: 1567494, DOI: 10.1002/art.1780350415.Peer-Reviewed Original ResearchConceptsInflammatory muscle diseaseJapanese patientsChronic interstitial lung diseaseMuscle diseaseAnti-PM/SclDifferent etiologic mechanismsTRNA synthetase antibodiesDistinct clinical subsetInterstitial lung diseasePM/DMControl patientsImmunogenetic backgroundOverlap syndromeClinical subsetsRheumatic diseasesSevere myositisAutoimmune responseRNP antibodiesAutoantibody specificitiesLung diseaseClinical correlationClinical significanceClinical comparisonSynthetase antibodiesEtiologic mechanisms
1988
The U2 small nuclear ribonucleoprotein particle as an autoantigen. Analysis with sera from patients with overlap syndromes.
Craft J, Mimori T, Olsen TL, Hardin JA. The U2 small nuclear ribonucleoprotein particle as an autoantigen. Analysis with sera from patients with overlap syndromes. Journal Of Clinical Investigation 1988, 81: 1716-1724. PMID: 2968364, PMCID: PMC442616, DOI: 10.1172/jci113511.Peer-Reviewed Original Research