1992
Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression.
Bell L, Luthringer D, Madri J, Warren S. Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression. Journal Of Clinical Investigation 1992, 89: 315-320. PMID: 1370299, PMCID: PMC442850, DOI: 10.1172/jci115578.Peer-Reviewed Original ResearchMeSH Keywords1-Sarcosine-8-Isoleucine Angiotensin IIAngiotensin IIAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAnimalsAortaCattleCell MovementCells, CulturedEnalaprilEndothelium, VascularGene Expression Regulation, ViralLisinoprilPlasminogen ActivatorsProtein KinasesProto-Oncogene Proteins pp60(c-src)Receptors, AngiotensinRNA, MessengerConceptsEndothelial cell migrationC-Src expressionCell migrationC-SrcProto-oncogene c-srcC-Src kinase activityPp60c-src expressionCoding sequenceKinase activityU-PABovine aortic endothelial cell migrationAngiotensin-converting enzyme inhibitor lisinoprilRetroviral vectorsProtein 3Plasminogen activatorStable infectionExpressionDenudation injuryPlasminogen activator activityActivatorActivity 2Cell expressionAngiotensin system inhibitionActivator activityEndothelial cell expression
1991
Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro.
Merwin J, Newman W, Beall L, Tucker A, Madri J. Vascular cells respond differentially to transforming growth factors beta 1 and beta 2 in vitro. American Journal Of Pathology 1991, 138: 37-51. PMID: 1846264, PMCID: PMC1886039.Peer-Reviewed Original ResearchConceptsBovine aortic endothelial cellsBovine aortic smooth muscle cellsGrowth factorGrowth factor beta 1Aortic smooth muscle cellsTGF-beta concentrationsSmooth muscle cellsProliferation of BAECsTGF-beta receptorsBovine aortic endothelial cell migrationType IAortic endothelial cellsTGF beta sCell typesMicrovascular endotheliumVascular cell typesReceptor assayMuscle cellsVascular cellsEndothelial cellsBeta 1Endothelial cell migrationBeta 2Angiogenic assaysBASMCs