1995
Modulation of cell spreading and migration by pp125FAK phosphorylation.
Sankar S, Mahooti-Brooks N, Hu G, Madri J. Modulation of cell spreading and migration by pp125FAK phosphorylation. American Journal Of Pathology 1995, 147: 601-8. PMID: 7677174, PMCID: PMC1870973.Peer-Reviewed Original ResearchConceptsPp125FAK tyrosine phosphorylationTyrosine phosphorylationCell migrationCell spreadingIntegrin-mediated signalingFocal adhesion kinaseKinase-negative mutantPp125FAK phosphorylationAdhesion kinaseMigration ratePhosphorylationCascade pathwayFaster migration rateControl cellsSlower migration rateType I collagenEnhanced levelsCellsI collagenFibronectinMigrationPp125FAKMutantsKinaseSignaling
1992
Platelet endothelial cell adhesion molecule, PECAM‐1, modulates cell migration
Schimmenti L, Yan H, Madri J, Albelda S. Platelet endothelial cell adhesion molecule, PECAM‐1, modulates cell migration. Journal Of Cellular Physiology 1992, 153: 417-428. PMID: 1429859, DOI: 10.1002/jcp.1041530222.Peer-Reviewed Original ResearchConceptsCell-cell adhesionCell-cell adhesion moleculesCell-cell contactPlatelet endothelial cell adhesion molecule-1Cell migrationIntegral membrane proteinsAdhesion moleculesPECAM-1 moleculesControl cellsCell surface adhesion moleculesModulates cell migrationNeomycin resistance geneEndothelial cell migrationMembrane proteinsCell adhesion moleculeEndothelial cellsExtracellular domainSurface adhesion moleculesNull cellsNIH/3T3 cellsResistance genesExtracellular matrixTransfectantsAdjacent cellsMigration assays