2009
Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects
Nath AK, Krauthammer M, Li P, Davidov E, Butler LC, Copel J, Katajamaa M, Oresic M, Buhimschi I, Buhimschi C, Snyder M, Madri JA. Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects. PLOS ONE 2009, 4: e4221. PMID: 19156209, PMCID: PMC2626248, DOI: 10.1371/journal.pone.0004221.Peer-Reviewed Original ResearchConceptsCardiovascular developmentMass spectrometry-based proteomicsSpectrometry-based proteomicsNormal cardiovascular developmentAdhesion/migrationHuman CHDsProteomic datasetsHeart developmentProtein clustersMurine embryosProtein pathwayMolecular pathwaysFunctional roleProteinEmbryonic survivalYolk sacProtein levelsIdentifies biomarkersCardiovascular defectsWestern blottingPathwayNovel avenuesEmbryosComplete understandingProtein biomarkers
1985
Congenital polycystic tumor of the atrioventricular node. Autopsy study with immunohistochemical findings suggesting endodermal derivation.
Duray P, Mark E, Barwick K, Madri J, Strom R. Congenital polycystic tumor of the atrioventricular node. Autopsy study with immunohistochemical findings suggesting endodermal derivation. Archives Of Pathology & Laboratory Medicine 1985, 109: 30-4. PMID: 2578779.Peer-Reviewed Original ResearchConceptsCongenital polycystic tumorPolycystic tumorSudden unexpected deathStandard histochemical stainsHeart blockAutopsy studyImmunohistochemical findingsUnexpected deathAtrioventricular nodeThymus glandImmunohistochemical labelingAtrioventricular junctionClinical standpointCarcinoembryonic antigen