2003
The evolving roles of cell surface proteases in health and disease: Implications for developmental, adaptive, inflammatory, and neoplastic processes
Madri JA. The evolving roles of cell surface proteases in health and disease: Implications for developmental, adaptive, inflammatory, and neoplastic processes. Current Topics In Developmental Biology 2003, 54: 391-410. PMID: 12696757, DOI: 10.1016/s0070-2153(03)54016-9.Peer-Reviewed Original ResearchConceptsCell surface proteolysisCell surface proteaseSurface proteolysisSurface proteaseDiversity of enzymesExtracellular matrix remodelingMaintenance of homeostasisBiological functionsMatrix remodelingAdaptive responseNormal homeostasisProteolytic responseCell proliferationProteolysisProtease activityEnzyme systemGeneral importanceHomeostasisProteaseCell attractionVascular systemDegenerative diseasesImportant processNeoplastic processComplement system
1994
The ENCEL system: a somatic cell protein delivery system.
Squinto S, Madri J, Kennedy S, Springhorn J. The ENCEL system: a somatic cell protein delivery system. In Vivo 1994, 8: 771-80. PMID: 7727724.Peer-Reviewed Original ResearchConceptsGene therapySuccessful gene therapyGene delivery vehiclesTherapeutic gene productsProtein delivery systemDelivery vehiclesTherapeutic proteinsUnique biological propertiesForeign genesSystemic deliveryDelivery systemDimensional culture systemsEngineering technologyPrime requirementSustained expressionBiological propertiesSomatic cellsSmall volumeCapillary-like structuresUnigraftSurface volumeTechnologyCulture systemDeliveryWide variety