2004
Non-enhancing de novo glioblastoma: report of two cases
Cohen-Gadol AA, DiLuna ML, Bannykh SI, Piepmeier JM, Spencer DD. Non-enhancing de novo glioblastoma: report of two cases. Neurosurgical Review 2004, 27: 281-285. PMID: 15449198, DOI: 10.1007/s10143-004-0346-5.Peer-Reviewed Original ResearchConceptsRing-enhancing lesionsLow-grade lesionsSecond patientMalignant gliomasRight medial temporal lobe lesionInitial MRI evaluationTraditional imaging findingsDe novo lesionsNew-onset seizuresMedial temporal lobe lesionsT2 signal changeRight precentral gyrusTemporal lobe lesionsMedial temporal lesionsRight frontal lesionDe novo glioblastomaEarly MRINovo lesionsNeurological examinationSubsequent resectionImaging findingsFirst patientMRI evaluationTumor suggestiveTemporal lesions
1990
A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury
Bracken M, Shepard M, Collins W, Holford T, Young W, Baskin D, Eisenberg H, Flamm E, Leo-Summers L, Maroon J, Marshall L, Perot P, Piepmeier J, Sonntag V, Wagner F, Wilberger J, Winn H. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury. New England Journal Of Medicine 1990, 322: 1405-1411. PMID: 2278545, DOI: 10.1056/nejm199005173222001.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryNeurologic recoverySafety of methylprednisoloneSystematic neurological examinationPlacebo-controlled trialHours of injuryMajor morbidityNeurologic outcomeControlled TrialsNeurological examinationIncomplete lesionsMotor functionMethylprednisoloneNaloxonePatientsBody weightSensory functionInjuryPlaceboInfusionBolusEffective remainsTreatmentDose
1988
Late neurological changes following traumatic spinal cord injury.
Piepmeier J, Jenkins N. Late neurological changes following traumatic spinal cord injury. Journal Of Neurosurgery 1988, 69: 399-402. PMID: 3404238, DOI: 10.3171/jns.1988.69.3.0399.Peer-Reviewed Original ResearchConceptsSpinal cord injuryTraumatic spinal cord injuryCord injuryNeurological functionPatient's spinal cord injuryFunctional neurological statusFrankel scaleNeurological statusNeurological examinationSpinal traumaYears postinjuryNeurological changesPatient statusInjuryMajority of improvementsPatientsExaminationSignificant changesStatusYearsPostinjuryHospitalTrauma
1987
Observations on the current treatment of low-grade astrocytic tumors of the cerebral hemispheres.
Piepmeier J. Observations on the current treatment of low-grade astrocytic tumors of the cerebral hemispheres. Journal Of Neurosurgery 1987, 67: 177-81. PMID: 3598677, DOI: 10.3171/jns.1987.67.2.0177.Peer-Reviewed Original ResearchConceptsLow-grade astrocytic tumorsComputerized tomographyCerebral hemispheresAstrocytic tumorsPreoperative neurological examinationUse of CTCurrent treatment methodsTreatment methodsPatient ageNeurological examinationTotal resectionTumor locationCurrent treatmentIntravenous administrationCT scanEarly diagnosisSurvival timeTumor enhancementContrast materialOptimal managementOnly factorPatientsLesionsOutcome statisticsTumors
1985
A phase I trial of naloxone treatment in acute spinal cord injury.
Flamm E, Young W, Collins W, Piepmeier J, Clifton G, Fischer B. A phase I trial of naloxone treatment in acute spinal cord injury. Journal Of Neurosurgery 1985, 63: 390-7. PMID: 3894597, DOI: 10.3171/jns.1985.63.3.0390.Peer-Reviewed Original ResearchConceptsGroup 2 patientsSpinal cord injuryAcute spinal cord injuryPhase I trialTime of admissionLoading doseCord injuryMaintenance doseI trialExperimental spinal cord injuryComplete neurological deficitGroup 1 patientsWeeks of admissionDose-related fashionTreatment of patientsOpiate antagonist naloxoneIncomplete deficitsMaintenance infusionNeurological deficitsNeurological statusNaloxone treatmentNeurological examinationAntagonist naloxoneInitial doseContinuous infusion