2020
Primary melanotic tumors of the nervous system: a consecutive case series
Grosshans H, Huttner A, Piepmeier J, Kaulen L, Fulbright R, Baehring J, Karschnia P. Primary melanotic tumors of the nervous system: a consecutive case series. European Journal Of Neurology 2020, 27: 2303-2307. PMID: 32654331, DOI: 10.1111/ene.14437.Peer-Reviewed Original ResearchConceptsPrimary melanotic tumorsNervous systemRelapsed diseaseClinical presentationMelanotic lesionsFavorable outcomeRadiation therapyPre-contrast T1-weighted imagingRelative incidenceMelanotic tumorsHomogenous contrast enhancementYale Cancer CenterAggressive surgical treatmentConsecutive case seriesPsammomatous melanotic schwannomaNervous system tumorsT1-weighted imagingT2-weighted imagingTumor mass effectMagnetic resonance imagingMelanin-containing cellsS100 positivitySurgical resectionSurgical treatmentTumor Registry
2012
Low-Grade Gliomas When and How to Treat
Omay SB, Piepmeier JM, Knisely JP. Low-Grade Gliomas When and How to Treat. Hematology/Oncology Clinics Of North America 2012, 26: 797-809. PMID: 22794284, DOI: 10.1016/j.hoc.2012.05.001.Peer-Reviewed Original ResearchConceptsSurgical resectionLow-grade gliomasPatient-specific variablesSame imaging techniqueRadiotherapeutic managementUncommon tumorClinical trialsOperative techniqueHistopathologic characterizationGrade gliomasOptimal managementAdditional studiesGliomasResectionAdequate samplesImaging techniquesPatientsPrognosisManagementTumorsTrialsNeurosurgical Approach
Moliterno JA, Patel TR, Piepmeier JM. Neurosurgical Approach. The Cancer Journal 2012, 18: 20-25. PMID: 22290253, DOI: 10.1097/ppo.0b013e3183243f6e3.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingTumor cellsResonance imagingAggressive surgical resectionAggressive tumor removalFunctional brain tissueFrequency of seizuresExtent of resectionGoal of surgeryInfiltrative tumor cellsPreferred initial stepFunctional magnetic resonance imagingProliferative tumor cellsAdjuvant therapyAggressive resectionSurgical resectionTumors recurCritical cortical regionsNeurologic impairmentTumor burdenProspective studyTumor resectionTumor removalInfiltrative tumorsMalignant gliomas
2004
Surgical Resection for Patients with Benign Primary Brain Tumors and Low Grade Gliomas
Piepmeier J, Baehring JM. Surgical Resection for Patients with Benign Primary Brain Tumors and Low Grade Gliomas. Journal Of Neuro-Oncology 2004, 69: 55-65. PMID: 15527080, DOI: 10.1023/b:neon.0000041871.46785.53.Peer-Reviewed Original ResearchConceptsPrimary brain tumorsBrain tumorsNeuroepithelial tumorsBenign primary brain tumorsMajority of patientsAdverse treatment effectsBenefits of therapyLow-grade tumorsLow-grade gliomasSurgical resectionInitial diagnosisMalignant degenerationPrimary neoplasmsSurgical managementSeizure focusBrain parenchymaChordoid gliomaNeurosurgical interventionThird ventricleChoroid plexusGrade gliomasTumorsUnknown originHeterogeneous groupCell pool
1999
Complications and Expected Outcome of Glioma Surgery
Vives K, Piepmeier J. Complications and Expected Outcome of Glioma Surgery. Journal Of Neuro-Oncology 1999, 42: 289-302. PMID: 10433111, DOI: 10.1023/a:1006163328765.Peer-Reviewed Original ResearchConceptsSurgical resectionKarnofsky performance statusGross total resectionManagement of patientsRisk of complicationsUse of radiotherapyRisk of recurrenceHigh-grade lesionsMaximum safe resectionCareful preoperative planningHigh-grade gliomasLow-grade gliomasPerformance statusExtensive surgeryMajor complicationsProlong survivalTotal resectionNeurologic impairmentGrade lesionsSafe resectionTreatment modalitiesIntraoperative mappingGlioma surgeryIntracerebral gliomasSurvival advantage