2022
Consistency between trials presented at conferences, their subsequent publications and press releases
Rowhani-Farid A, Hong K, Grewal M, Reynolds J, Zhang A, Wallach J, Ross J. Consistency between trials presented at conferences, their subsequent publications and press releases. BMJ Evidence-Based Medicine 2022, 28: 95-102. PMID: 36357160, PMCID: PMC10086295, DOI: 10.1136/bmjebm-2022-111989.Peer-Reviewed Original ResearchConceptsClinical trialsConference abstractsTrial resultsEndpoint definitionsPrimary efficacy end pointEnd pointEfficacy end pointPrimary efficacy endpointClinical Trials RegistryMedical conferencesMultiple logistic regressionCross-sectional analysisSafety endpointEfficacy endpointPeer-reviewed journalsTrial abstractsTrials RegistryTrial characteristicsConsistency of reportingSample sizePrimary analysisSecondary analysisInternational medical conferencesLogistic regressionStudy design
2020
Non-inferiority trials using a surrogate marker as the primary endpoint: An increasing phenotype in cardiovascular trials
Bikdeli B, Caraballo C, Welsh J, Ross JS, Kaul S, Stone GW, Krumholz HM. Non-inferiority trials using a surrogate marker as the primary endpoint: An increasing phenotype in cardiovascular trials. Clinical Trials 2020, 17: 723-728. PMID: 32838556, PMCID: PMC8088773, DOI: 10.1177/1740774520949157.Peer-Reviewed Original ResearchConceptsNon-inferiority trialPrimary endpointClinical outcome trialsNon-inferiority marginSurrogate markerNon-inferiority designCardiovascular trialsOutcome trialsClinical outcomesDefinitive clinical outcome trialsNon-inferiority criteriaStudy protocolSurrogate outcomesBACKGROUND/Median numberSurrogate endpointsPrimary analysisCardiovascular interventionsCardiovascular medicineTrialsEndpointClinical interpretationOutcomesMarkersIntervention
2010
Laboratory Test Ordering at Physician Offices with and without On-Site Laboratories
Bishop TF, Federman AD, Ross JS. Laboratory Test Ordering at Physician Offices with and without On-Site Laboratories. Journal Of General Internal Medicine 2010, 25: 1057-1063. PMID: 20532656, PMCID: PMC2955467, DOI: 10.1007/s11606-010-1409-7.Peer-Reviewed Original ResearchConceptsProstate-specific antigenConfidence intervalsNational Ambulatory Medical Care SurveyAmbulatory Medical Care SurveyPrimary care physiciansDesignCross-sectional studyPhysician ownersGroup practiceHealth care servicesLaboratory testsCommon laboratory testsExcess healthcare spendingGroup practice physiciansCare physiciansBlood countCare SurveyPhysician's officePrimary analysisPractice characteristicsCare servicesSecondary analysisKey ResultsThereSite laboratoryVisitsAOR