2024
Outcomes of Reduced Elective Nodal Radiation Dose for Laryngeal, Hypopharyngeal and p16 Negative Oropharyngeal Cancers
Zakeri K, Shang T, Yu Y, Chen L, Shamseddine A, Kang J, Tsai C, Sherman E, Wong R, McBride S, Gelblum D, Riaz N, Lee N. Outcomes of Reduced Elective Nodal Radiation Dose for Laryngeal, Hypopharyngeal and p16 Negative Oropharyngeal Cancers. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e807. DOI: 10.1016/j.ijrobp.2024.07.1772.Peer-Reviewed Original ResearchP16-negative oropharyngeal squamous cell carcinomaNegative oropharyngeal squamous cell carcinomasOropharyngeal squamous cell carcinomaDistant recurrenceSquamous cell carcinomaNodal recurrenceRadiotherapy doseLocoregional recurrenceP16 statusCell carcinomaHypopharynx cancerP16-negative oropharyngeal cancerHead and neck cancer patientsRadiation doseElective nodal volumesP16-negative diseaseNode-positive diseaseDecrease treatment toxicityNeck cancer patientsPrimary outcome measureConcurrent cetuximabConcurrent chemotherapyLocoregional controlMedian followNodal disease
2021
Postoperative PET/CT for detection of early recurrence (ER) after surgery for squamous cell carcinomas (SCC) of the oral cavity (OC).
Yu Y, Schöder H, Kang J, McBride S, Tsai C, Chen L, Zakeri K, Gelblum D, Boyle J, Cracchiolo J, Cohen M, Singh B, Ganly I, Patel S, Michel L, Dunn L, Pfister D, Wong R, Riaz N, Lee N. Postoperative PET/CT for detection of early recurrence (ER) after surgery for squamous cell carcinomas (SCC) of the oral cavity (OC). Journal Of Clinical Oncology 2021, 39: 6060-6060. DOI: 10.1200/jco.2021.39.15_suppl.6060.Peer-Reviewed Original ResearchPostoperative PET/CTIntermediate risk factorsSquamous cell carcinomaHigh-risk factorsPET/CTPT3-4 diseasePositive surgical marginsEarly recurrenceSurgical marginsExtranodal extensionLymphovascular invasionPerineural invasionRisk factorsOral cavityPostoperative radiotherapyOverall survivalPostoperative radiationPET/CT planningDistant metastasis-free survivalImproved disease-free survivalClinicopathologic risk factorsClose surgical marginsDisease-free survivalSalvage therapyDistant recurrence