Kit Regulates HSC Engraftment across the Human-Mouse Species Barrier
Cosgun KN, Rahmig S, Mende N, Reinke S, Hauber I, Schäfer C, Petzold A, Weisbach H, Heidkamp G, Purbojo A, Cesnjevar R, Platz A, Bornhäuser M, Schmitz M, Dudziak D, Hauber J, Kirberg J, Waskow C. Kit Regulates HSC Engraftment across the Human-Mouse Species Barrier. Cell Stem Cell 2014, 15: 227-238. PMID: 25017720, DOI: 10.1016/j.stem.2014.06.001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineageCrosses, GeneticEnzyme-Linked Immunosorbent AssayFetal BloodGene Expression RegulationHematopoietic Stem Cell TransplantationHematopoietic Stem CellsHumansLymphocytesMiceMice, Inbred C57BLMice, TransgenicMutationRNA, MessengerSpecies SpecificityStem Cell FactorThymocytesTime FactorsClonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells
Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun KN, Alexopoulou D, Lakshmanaperumal N, Henry I, Dahl A, Waskow C. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. Journal Of Experimental Medicine 2014, 211: 209-215. PMID: 24446490, PMCID: PMC3920556, DOI: 10.1084/jem.20131115.Peer-Reviewed Original ResearchAnimalsCell SeparationColony-Forming Units AssayHematopoiesisHematopoietic Stem Cell TransplantationHematopoietic Stem CellsMiceMice, Inbred C57BLProto-Oncogene Proteins c-kitSignal Transduction