2018
Spine Patterning Is Guided by Segmentation of the Notochord Sheath
Wopat S, Bagwell J, Sumigray KD, Dickson AL, Huitema LFA, Poss KD, Schulte-Merker S, Bagnat M. Spine Patterning Is Guided by Segmentation of the Notochord Sheath. Cell Reports 2018, 22: 2026-2038. PMID: 29466731, PMCID: PMC5860813, DOI: 10.1016/j.celrep.2018.01.084.Peer-Reviewed Original ResearchConceptsNotochord sheathTissue-specific manipulationActivation of NotchZebrafish notochordCentrum formationVertebral patterningOuter epithelial cell layerSheath cellsSegmentation defectsAxial structuresEpithelial cell layerNotochordPatterningIVD areaZebrafish spineDomainCell layerNotchCentraOsteoblastsSheathCellsActivation
2016
Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis
Rogers EM, Spracklen AJ, Bilancia CG, Sumigray KD, Allred SC, Nowotarski SH, Schaefer KN, Ritchie BJ, Peifer M. Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis. Molecular Biology Of The Cell 2016, 27: 2613-2631. PMID: 27385341, PMCID: PMC4985262, DOI: 10.1091/mbc.e16-05-0292.Peer-Reviewed Original ResearchConceptsF-actin-binding domainCell biological rolesCell shape changesDifferent protein motifsSeries of mutantsTyrosine kinase domainAbl functionActin regulationDrosophila morphogenesisEmbryonic morphogenesisProtein motifsAbelson familyPXXP motifInteraction domainKinase domainAbelson kinaseLinker regionKey regulatorAbl SH3Biological roleCellular behaviorMorphogenesisCell behaviorNormal developmentSH3
2015
Chapter Twelve Cell Adhesion in Epidermal Development and Barrier Formation
Sumigray KD, Lechler T. Chapter Twelve Cell Adhesion in Epidermal Development and Barrier Formation. Current Topics In Developmental Biology 2015, 112: 383-414. PMID: 25733147, PMCID: PMC4737682, DOI: 10.1016/bs.ctdb.2014.11.027.Peer-Reviewed Original ResearchMeSH KeywordsAdherens JunctionsAnimalsCell AdhesionCell Adhesion MoleculesCell DifferentiationEpidermal CellsEpidermisHumansSignal TransductionConceptsEpidermal developmentAdhesion proteinsCell-cell adhesionCell-cell junctionsCell biological studiesCell adhesion proteinsNoncanonical roleComposite proteinsAdhesive functionBarrier formationGrowth controlCell adhesionTissue physiologyProteinBiological studiesJunctional systemEpidermisTransductionAdhesionStructural integrityDifferentiationPhysiologyRoleFunctionJunction
2010
Dissecting cell adhesion cross-talk with micropatterns
Sumigray KD, Lechler T. Dissecting cell adhesion cross-talk with micropatterns. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 13199-13200. PMID: 20639470, PMCID: PMC2922164, DOI: 10.1073/pnas.1008253107.Peer-Reviewed Original Research