2015
Distinct promoter activation mechanisms modulate noise-driven HIV gene expression
Chavali AK, Wong VC, Miller-Jensen K. Distinct promoter activation mechanisms modulate noise-driven HIV gene expression. Scientific Reports 2015, 5: 17661. PMID: 26666681, PMCID: PMC4678399, DOI: 10.1038/srep17661.Peer-Reviewed Original Research
2012
Chromatin accessibility at the HIV LTR promoter sets a threshold for NF-κB mediated viral gene expression
Miller-Jensen K, Dey SS, Pham N, Foley JE, Arkin AP, Schaffer DV. Chromatin accessibility at the HIV LTR promoter sets a threshold for NF-κB mediated viral gene expression. Integrative Biology 2012, 4: 661-671. PMID: 22555315, PMCID: PMC3362694, DOI: 10.1039/c2ib20009k.Peer-Reviewed Original ResearchConceptsChromatin accessibilityGene expressionChromatin environmentIntegration sitesHigher-order chromatin structureDifferent genomic environmentsLTR promoterRepressive histone marksDifferent chromatin environmentsOrder chromatin structureGene expression regulationTranscription factor inputsSame transcription factorDifferential gene expressionLevels of RelASelective gene expressionViral gene expressionViral integration sitesTranscription factor activationHIV gene regulationGenomic environmentHIV LTR promoterHistone marksChromatin featuresChromatin structure
2009
Control of Stochastic Gene Expression by Host Factors at the HIV Promoter
Burnett JC, Miller-Jensen K, Shah PS, Arkin AP, Schaffer DV. Control of Stochastic Gene Expression by Host Factors at the HIV Promoter. PLOS Pathogens 2009, 5: e1000260. PMID: 19132086, PMCID: PMC2607019, DOI: 10.1371/journal.ppat.1000260.Peer-Reviewed Original Research