2024
Causes of death and patterns of metastatic disease at the end of life for patients with advanced melanoma in the immunotherapy era
Lee D, McNamara M, Yang A, Yaskolko M, Kluger H, Tran T, Olino K, Clune J, Sznol M, Ishizuka J. Causes of death and patterns of metastatic disease at the end of life for patients with advanced melanoma in the immunotherapy era. Pigment Cell & Melanoma Research 2024, 37: 847-853. PMID: 39073002, DOI: 10.1111/pcmr.13188.Peer-Reviewed Original ResearchSite of metastasisPattern of metastatic diseaseMelanoma mortalityRetrospective observational cohort studyCause of cancer mortalityDistant lymph nodesObservational cohort studyDiagnosis to deathImmunotherapy eraAdvanced melanomaMetastatic diagnosisMetastatic diseaseMetastatic melanomaImmunotherapy treatmentRespiratory failureCause of deathMedian timeLymph nodesTherapeutic advancesCohort studyMelanomaImmunotherapyMechanism of deathPatientsEnd of life
2022
Unmeasured factors are associated with the use of completion lymph node dissection (CLND) in melanoma
Leonard L, Beaty L, Thomas M, Quinn C, Colborn K, de Araujo T, Torphy R, Assumpção L, Olino K, Studts C, Franco S, McCarter M, Stewart C, Gleisner A. Unmeasured factors are associated with the use of completion lymph node dissection (CLND) in melanoma. Journal Of Surgical Oncology 2022, 127: 716-726. PMID: 36453464, DOI: 10.1002/jso.27153.Peer-Reviewed Original ResearchConceptsCompletion lymph node dissectionSentinel lymph nodesPositive sentinel lymph nodesLymph node dissectionNode dissectionMultivariable mixed-effects logistic regression modelGovernment-based insuranceNational Cancer DatabasePrimary tumor locationStage III melanomaEffect of patientContribution of patientMixed effects logistic regression modelsLogistic regression modelsTumor factorsOlder patientsSurvival benefitLymph nodesSurgical excisionStandard treatmentTumor locationCancer DatabasePatient variablesPatientsLower limbs
2021
Methods of Sentinel Lymph Node Identification in Auricular Melanoma
Noorbakhsh S, Papageorge M, Maina RM, Baumann R, Moores C, Weiss SA, Pucar D, Ariyan S, Olino K, Clune J. Methods of Sentinel Lymph Node Identification in Auricular Melanoma. Plastic & Reconstructive Surgery Global Open 2021, 9: e4004. PMID: 34938645, PMCID: PMC8687720, DOI: 10.1097/gox.0000000000004004.Peer-Reviewed Original ResearchAuricular melanomaSentinel nodesLymphatic drainage patternsIntraoperative identificationSentinel lymphPlanar lymphoscintigraphyPreoperative imagingPreoperative mappingSPECT-CTSentinel lymph node identificationCareful intraoperative evaluationMore sentinel nodesSentinel node identificationSentinel lymph nodesLymph node identificationSingle photon emissionMicrometastatic diseaseLymph nodesRetrospective reviewPreoperative identificationIntraoperative evaluationComputerized tomographyMelanomaNode identificationLymphoscintigraphy
2010
Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis
Winter JM, Cameron JL, Olino K, Herman JM, de Jong MC, Hruban RH, Wolfgang CL, Eckhauser F, Edil BH, Choti MA, Schulick RD, Pawlik TM. Clinicopathologic Analysis of Ampullary Neoplasms in 450 Patients: Implications for Surgical Strategy and Long-Term Prognosis. Journal Of Gastrointestinal Surgery 2010, 14: 379-387. PMID: 19911239, DOI: 10.1007/s11605-009-1080-7.Peer-Reviewed Original ResearchConceptsLymph node metastasisAmpullary neoplasmsNode metastasisSurgical resectionTumor sizeInvasive adenocarcinomaMicroscopic vessel invasionInitial surgical procedureMedian tumor sizeOutcomes of patientsPoor histologic gradeLong-term prognosisSingle-institution databaseRegional lymph nodesAmpulla of VaterEarly invasive adenocarcinomaDepth of invasionMethodsBetween 1970Metastatic diseaseRadical resectionAmpullary adenomasClinicopathologic factorsLymph nodesClinicopathologic analysisPerineural invasion