Integrin α2 Mediates Selective Metastasis to the Liver
Yoshimura K, Meckel KF, Laird LS, Chia CY, Park JJ, Olino KL, Tsunedomi R, Harada T, Iizuka N, Hazama S, Kato Y, Keller JW, Thompson JM, Chang F, Romer LH, Jain A, Iacobuzio-Donahue C, Oka M, Pardoll DM, Schulick RD. Integrin α2 Mediates Selective Metastasis to the Liver. Cancer Research 2009, 69: 7320-7328. PMID: 19738067, PMCID: PMC4857201, DOI: 10.1158/0008-5472.can-09-0315.Peer-Reviewed Original ResearchConceptsHepatic metastasesColorectal cancerPrimary colorectal cancerHuman colorectal cancerIntegrin alpha2Organ-specific metastasisLiver metastasesLung metastasesAntibody blockadeIntegrin alpha2 expressionSelective metastasisIndividual patientsB16 melanomaCollagen type IVMetastasisAlpha2 expressionCell membrane moleculesMetastatic processB16-F0CancerType IVPossible targetsIntegrin α2LiverAlpha2The Current Management of Choledochal Cysts
Edil BH, Olino K, Cameron JL. The Current Management of Choledochal Cysts. Advances In Surgery 2009, 43: 221-232. PMID: 19845181, DOI: 10.1016/j.yasu.2009.02.007.ChaptersConceptsCholedochal cystCholedochal cyst diseaseLate complicationsCyst diseasePediatric populationSurgical excisionBiliary diseaseLiver fibrosisComplete excisionInterventional techniquesGeneral surgeonsAdult populationCurrent managementMalignant transformationCystsDiseaseType IVComplicationsExcisionDiagnosisPatientsFibrosisMRCPPopulationCancer