2012
Genome-wide association study of Tourette's syndrome
Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrío GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A, Hardy J, Strengman E, Ophoff R, Wagner M, Moessner R, Mirel D, Posthuma D, Sabatti C, Eskin E, Conti D, Knowles J, Ruiz-Linares A, Rouleau G, Purcell S, Heutink P, Oostra B, McMahon W, Freimer N, Cox N, Pauls D. Genome-wide association study of Tourette's syndrome. Molecular Psychiatry 2012, 18: 721-728. PMID: 22889924, PMCID: PMC3605224, DOI: 10.1038/mp.2012.69.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAttention Deficit Disorder with HyperactivityCase-Control StudiesChromosomes, Human, Pair 9FemaleFibrillar CollagensGenetic Predisposition to DiseaseGenome-Wide Association StudyGenotypeHumansInternational CooperationMaleMeta-Analysis as TopicObsessive-Compulsive DisorderPolymorphism, Single NucleotideTourette SyndromeWhite PeopleYoung AdultConceptsGenome-wide association studiesFirst genome-wide association studyAssociation studiesTop signalsFull genetic architectureAncestry-matched controlsEuropean ancestry samplesGenetic architectureGWAS dataComplex inheritanceEuropean-derived populationsSusceptibility variantsSusceptibility genesEventual identificationEuropean ancestryCosta RicaChromosome 9q32Familial recurrence rateNorth AmericaComplete understandingAmerican populationCentral ValleyNeuropsychiatric diseasesDevelopmental disordersGenes
1999
Genealogy reconstruction from short tandem repeat genotypes in an Amazonian population
Calafell F, Shuster A, Speed W, Kidd J, Black F, Kidd K. Genealogy reconstruction from short tandem repeat genotypes in an Amazonian population. American Journal Of Biological Anthropology 1999, 108: 137-146. PMID: 9988377, DOI: 10.1002/(sici)1096-8644(199902)108:2<137::aid-ajpa1>3.0.co;2-k.Peer-Reviewed Original Research
1992
Presymptomatic testing using DNA markers for individuals at risk for familial multiple endocrine neoplasia 2A
Lichter J, Wu J, Genel M, Flynn S, Pakstis A, Kidd J, Kidd K. Presymptomatic testing using DNA markers for individuals at risk for familial multiple endocrine neoplasia 2A. The Journal Of Clinical Endocrinology & Metabolism 1992, 74: 368-373. PMID: 1346145, DOI: 10.1210/jcem.74.2.1346145.Peer-Reviewed Original Research
1988
Migraine and depression: Association and familial transmission
Merikangas K, Risch N, Merikangas J, Weissman M, Kidd K. Migraine and depression: Association and familial transmission. Journal Of Psychiatric Research 1988, 22: 119-129. PMID: 3404480, DOI: 10.1016/0022-3956(88)90076-3.Peer-Reviewed Original Research
1987
Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression
Price R, Kidd K, Weissman M. Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression. JAMA Psychiatry 1987, 44: 434-440. PMID: 3472494, DOI: 10.1001/archpsyc.1987.01800170048008.Peer-Reviewed Original ResearchConceptsEarly onsetMajor depressionPanic disorderLate-onset depressionPrevalence of depressionElevation of riskFamilies of probandsYale Family StudyEtiologic homogeneityHigh riskPatterns of transmissionOlder age cohortsRestriction of analysisDepressionPopulation ratesFamily studiesProbandsOnsetDisordersAge cohortsRiskGenetic modelsSample sizeCohortPrevalenceSeverity of Tourette's Syndrome in One Large Kindred: Implication for Determination of Disease Prevalence Rate
Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd K. Severity of Tourette's Syndrome in One Large Kindred: Implication for Determination of Disease Prevalence Rate. JAMA Neurology 1987, 44: 268-269. PMID: 3469941, DOI: 10.1001/archneur.1987.00520150024013.Peer-Reviewed Original ResearchConceptsChronic motor ticsPrevalence ratesTourette syndromeSeverity of illnessAccurate prevalence ratesDisease prevalence ratesAutosomal dominant transmissionMotor ticsTic disordersVocal ticsMedical attentionStandardized questionnaireMedical careSyndromeLarge MennoniteApparent autosomal dominant transmissionDominant transmissionFamily membersSeverityMost casesIllnessCareBipolar affective disorders linked to DNA markers on chromosome 11
Egeland J, Gerhard D, Pauls D, Sussex J, Kidd K, Alien C, Hostetter A, Housman D. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 1987, 325: 783-787. PMID: 2881209, DOI: 10.1038/325783a0.Peer-Reviewed Original Research
1986
Gilles de la Tourette's Syndrome and Attention Deficit Disorder With Hyperactivity: Evidence Against a Genetic Relationship
Pauls D, Hurst C, Kruger S, Leckman J, Kidd K, Cohen D. Gilles de la Tourette's Syndrome and Attention Deficit Disorder With Hyperactivity: Evidence Against a Genetic Relationship. JAMA Psychiatry 1986, 43: 1177-1179. PMID: 3465279, DOI: 10.1001/archpsyc.1986.01800120063012.Peer-Reviewed Original ResearchFamilial Tourette's syndrome: report of a large pedigree and potential for linkage analysis.
Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd J, Kidd K. Familial Tourette's syndrome: report of a large pedigree and potential for linkage analysis. Neurology 1986, 36: 772-6. PMID: 3458031, DOI: 10.1212/wnl.36.6.772.Peer-Reviewed Original ResearchConceptsChronic motor ticsTourette syndromeDefinite Tourette's syndromePermanent lymphoblastoid cell linesDSM-III criteriaAutosomal dominant patternFamily membersClinical featuresMotor ticsVocal ticsLymphoblastoid cell linesStandardized questionnaireLarge MennoniteCell linesSyndromeDominant patternIndependent ratingsUnderstanding the Clinical Heterogeneity of Major Depression Using Family Data
Weissman M, Merikangas K, Priya W, Kidd K, Prusoff B, Leckman J, Pauls D. Understanding the Clinical Heterogeneity of Major Depression Using Family Data. JAMA Psychiatry 1986, 43: 430-434. PMID: 3964021, DOI: 10.1001/archpsyc.1986.01800050028003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAlcoholismAnxiety DisordersDepressive DisorderFemaleHumansMaleRiskSuicideConceptsMajor depressionSymptom patternsHistory of hospitalizationClinical presentationClinical severityRecurrent depressionSecondary alcoholismClinical heterogeneitySuicidal ideationAnxiety disordersDepressionFamilial aggregationEarly ageDisordersCombination of criteriaAgeSubgroupsRiskOnsetPutative subgroupsHospitalizationLinkage Analysis in a Family with Dominantly Inherited Torsion Dystonia: Exclusion of the Pro-Opiomelanocortin and Glutamic Acid Decarboxylase Genes and Other Chromosomal Regions Using DNA Polymorphisms
Breakefield X, Bressman S, Kramer P, Ozelius L, Moskowitz C, Tanzi R, Brin M, Hobbs W, Kaufman D, Tobin A, Kidd K, Fahn S, Gusella J. Linkage Analysis in a Family with Dominantly Inherited Torsion Dystonia: Exclusion of the Pro-Opiomelanocortin and Glutamic Acid Decarboxylase Genes and Other Chromosomal Regions Using DNA Polymorphisms. Journal Of Neurogenetics 1986, 3: 159-175. PMID: 3016220, DOI: 10.3109/01677068609106846.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolChromosome DeletionChromosome MappingCloning, MolecularDNADNA Restriction EnzymesDystonia Musculorum DeformansFemaleGenesGenes, DominantGenetic LinkageGlutamate DecarboxylaseHumansLymphocytesMaleMiddle AgedPedigreePolymorphism, GeneticPro-OpiomelanocortinConceptsLinkage analysisGlutamic acid decarboxylase geneRestriction fragment length polymorphismDecarboxylase geneDNA sequencesMode of inheritanceChromosomal regionsDNA polymorphismsFragment length polymorphismDefective geneLod score methodGenesDNA probesLength polymorphismLymphoblast linesInheritanceDisease statesAutosomal dominant modeGene penetranceSequenceFamilyPolymorphismGenomeAcid decarboxylaseRequisite assumptions
1985
A Twin Study of Tourette Syndrome
Price R, Kidd K, Cohen D, Pauls D, Leckman J. A Twin Study of Tourette Syndrome. JAMA Psychiatry 1985, 42: 815-820. PMID: 3860194, DOI: 10.1001/archpsyc.1985.01790310077011.Peer-Reviewed Original Research
1984
Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity
Weissman M, Wickramaratne P, Merikangas K, Leckman J, Prusoff B, Caruso K, Kidd K, Gammon G. Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity. JAMA Psychiatry 1984, 41: 1136-1143. PMID: 6508504, DOI: 10.1001/archpsyc.1984.01790230022003.Peer-Reviewed Original ResearchConceptsAge of onsetMajor depressionNormal control subjectsRelatives of probandsFamilial loadingControl subjectsEarly-onset depressionFirst-degree relativesYears of ageHigh familial loadingHigh riskNormal subjectsSpecificity of transmissionEarly adulthoodDepressionProbandsAgeMore studiesFamily studiesYoung personOnsetLater ageHomogeneous disorderSubjectsInverse relationshipAmish study, IV: Genetic linkage study of pedigrees of bipolar probands
Kidd K, Egeland J, Molthan L, Pauls D, Kruger S, Messner K. Amish study, IV: Genetic linkage study of pedigrees of bipolar probands. American Journal Of Psychiatry 1984, 141: 1042-1048. PMID: 6331772, DOI: 10.1176/ajp.141.9.1042.Peer-Reviewed Original ResearchPsychopathology in the Children (Ages 6–18) of Depressed and Normal Parents
WEISSMAN M, PRUSOFF B, GAMMON G, MERIKANGAS K, LECKMAN J, KIDD K. Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 78-84. PMID: 6693680, DOI: 10.1097/00004583-198401000-00011.Peer-Reviewed Original ResearchConceptsDSM-III diagnosesFirst-degree relativesMajor depressionPsychiatric disordersProbands' first-degree relativesChildren of probandsCommon psychiatric disordersDirect interview studyFamily history studyClinical statusPsychiatric illnessNormal controlsDepressed probandsPsychological symptomsSuicidal behaviorEarly onsetDiagnosisDepressionSignificant predictorsProbandsAttention deficitsChildrenRiskEmotional problemsNormal parentsSegregation analyses of stuttering
Cox N, Kramer P, Kidd K, Rao D. Segregation analyses of stuttering. Genetic Epidemiology 1984, 1: 245-253. PMID: 6549563, DOI: 10.1002/gepi.1370010304.Peer-Reviewed Original ResearchConceptsFirst-degree relatives
1983
Recovery and Persistence of Stuttering among Relatives of Stutterers
Seider R, Kidd K, Gladstien K. Recovery and Persistence of Stuttering among Relatives of Stutterers. Journal Of Speech-language & Hearing Disorders 1983, 48: 402-409. PMID: 6645435, DOI: 10.1044/jshd.4804.402.Peer-Reviewed Original Research
1982
Variability in Rates of Affective Disorders in Relatives of Depressed and Normal Probands
Weissman M, Kidd K, Prusoff B. Variability in Rates of Affective Disorders in Relatives of Depressed and Normal Probands. JAMA Psychiatry 1982, 39: 1397-1403. PMID: 7149900, DOI: 10.1001/archpsyc.1982.04290120033006.Peer-Reviewed Original ResearchThe effects of requisite assumptions on linkage analyses of manic-depressive illness with HLA.
Kruger S, Turner W, Kidd K. The effects of requisite assumptions on linkage analyses of manic-depressive illness with HLA. Biological Psychiatry 1982, 17: 1081-99. PMID: 6959652.Peer-Reviewed Original ResearchThe Epidemiology of Tourette's Syndrome: A Pilot Study
Jagger J, Prusoff B, Cohen D, Kidd K, Carbonari C, John K. The Epidemiology of Tourette's Syndrome: A Pilot Study. Schizophrenia Bulletin 1982, 8: 267-278. PMID: 6955942, DOI: 10.1093/schbul/8.2.267.Peer-Reviewed Original ResearchConceptsSyndrome patientsDiagnosis of TSTourette syndrome patientsTourette Syndrome AssociationUnpleasant side effectsMost patientsSelf-report questionnairesSyndrome AssociationEffective treatmentPatient membersSide effectsAlternative treatmentTourette syndromeDiscontinued usePatientsPilot studyHaloperidolSyndromeTreatmentQuestionnaireAttentional difficultiesSymptomsEpidemiologyDiagnosis