2022
Hepatectomy is associated with improved oncologic outcomes in recurrent colorectal liver metastases: A propensity-matched analysis
Sutton T, Wong L, Walker B, Dewey E, Eil R, Lopez C, Kardosh A, Chen E, Rocha F, Billingsley K, Mayo S. Hepatectomy is associated with improved oncologic outcomes in recurrent colorectal liver metastases: A propensity-matched analysis. Surgery 2022, 173: 1314-1321. PMID: 36435651, DOI: 10.1016/j.surg.2022.10.019.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesPost-recurrence overall survivalRepeat hepatic resectionRecurrent colorectal liver metastasesHepatic resectionLiver metastasesSystemic treatmentOverall survivalIntrahepatic recurrenceOncologic outcomesSystemic therapyMedian post-recurrence overall survivalRetrospective single-institution cohort studySingle-institution cohort studyCurative-intent hepatectomyImproved oncologic outcomesPerioperative systemic therapyRelevant clinicopathologic variablesSignificant clinicopathologic differencesPropensity-matched analysisRole of resectionCox proportional hazardsLiver recurrencePerioperative chemotherapyCohort study
2020
Effect of Time to Surgery of Colorectal Liver Metastases on Survival
Chen EY, Mayo SC, Sutton T, Kearney MR, Kardosh A, Vaccaro GM, Billingsley KG, Lopez CD. Effect of Time to Surgery of Colorectal Liver Metastases on Survival. Journal Of Gastrointestinal Cancer 2020, 52: 169-176. PMID: 32086781, PMCID: PMC7900034, DOI: 10.1007/s12029-020-00372-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantColorectal NeoplasmsDisease-Free SurvivalFemaleFollow-Up StudiesHepatectomyHumansKaplan-Meier EstimateLiver NeoplasmsMaleMiddle AgedNeoadjuvant TherapyNeoplasm Recurrence, LocalPrognosisRetrospective StudiesTime FactorsTime-to-TreatmentYoung AdultConceptsColorectal liver metastasesLong-term OSPostoperative overall survivalOverall survivalLonger TTSLiver metastasesWorse survivalDiagnosis of CLMLong-term survivorsResultsTwo hundred eightyRisk of recurrenceComprehensive cancer centerHigh disease burdenSpecific primary tumorsShorter TTSPerioperative chemotherapyPostoperative chemotherapyPerioperative treatmentResection marginsCancer CenterMetastasis characteristicsInstitutional databasePrimary tumorDisease burdenSimilar survivalHepatic arterial infusion pump chemotherapy combined with systemic therapy for patients with advanced colorectal liver metastases: Outcomes in a newly established program
Walker B, Billingsley K, Sutton T, Zarour L, Kolbeck K, Korngold E, Chen E, Kardosh A, Herzig D, Tsikitis V, Nabavizadeh N, Dewey E, Lopez C, Mayo S. Hepatic arterial infusion pump chemotherapy combined with systemic therapy for patients with advanced colorectal liver metastases: Outcomes in a newly established program. Hepato Pancreato Biliary 2020, 22: s123-s124. DOI: 10.1016/j.hpb.2020.04.630.Peer-Reviewed Original Research
2019
Safety and Feasibility of Hepatic Artery Infusion Pump Chemotherapy for Unresectable Colorectal Liver Metastases: A Multicenter, Retrospective Cohort Study
Muaddi H, Fields R, Aucejo F, Billingsley K, Walker B, D'Angelica M, Latchana N, Roke R, Ko Y, Williams G, Acevedo-Moreno L, Mayo S, Karanicolas P. Safety and Feasibility of Hepatic Artery Infusion Pump Chemotherapy for Unresectable Colorectal Liver Metastases: A Multicenter, Retrospective Cohort Study. Journal Of The American College Of Surgeons 2019, 229: s184. DOI: 10.1016/j.jamcollsurg.2019.08.406.Peer-Reviewed Original Research
2014
Modern Technical Approaches in Resectional Hepatic Surgery
Michalski CW, Billingsley KG. Modern Technical Approaches in Resectional Hepatic Surgery. Surgical Oncology Clinics Of North America 2014, 24: 57-72. PMID: 25444469, DOI: 10.1016/j.soc.2014.09.007.Peer-Reviewed Original ResearchConceptsLiver resectionLiver surgeryPreoperative portal vein embolizationModern liver surgeryColorectal liver metastasesExtensive liver resectionPreoperative patient selectionPortal vein embolizationGroup of patientsBlood-sparing techniquesOverview of indicationsLiver metastasesPerioperative managementVein embolizationLow morbidityPatient selectionMultimodal treatmentHepatic surgeryResectionAdjunctive techniquesSurgeryModern technical approachesSafe performanceEmbolizationMorbidity
2013
Safety and Outcomes Following Resection of Colorectal Liver Metastases in the Era of Current Perioperative Chemotherapy
Gur I, Diggs B, Wagner J, Vaccaro G, Lopez C, Sheppard B, Orloff S, Billingsley K. Safety and Outcomes Following Resection of Colorectal Liver Metastases in the Era of Current Perioperative Chemotherapy. Journal Of Gastrointestinal Surgery 2013, 17: 2133-2142. PMID: 24091909, DOI: 10.1007/s11605-013-2295-1.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesPreoperative chemotherapyPerioperative chemotherapyOverall survivalLiver metastasesAdvanced ageResectable colorectal liver metastasesPreoperative portal vein embolizationShorter disease-free intervalAcademic oncology centerOutcomes Following ResectionThirty-day mortalityDisease-free intervalHigh-risk patientsPortal vein embolizationSubset of patientsPoor overall survivalLiver recurrenceSynchronous diseaseEleven patientsPostoperative complicationsRepeat resectionLiver resectionVein embolizationRetrospective review
2011
Outcome After Laparoscopic Radiofrequency Ablation of Technically Resectable Colorectal Liver Metastases
Hammill C, Billingsley K, Cassera M, Wolf R, Ujiki M, Hansen P. Outcome After Laparoscopic Radiofrequency Ablation of Technically Resectable Colorectal Liver Metastases. Annals Of Surgical Oncology 2011, 18: 1947-1954. PMID: 21399885, DOI: 10.1245/s10434-010-1535-9.Peer-Reviewed Original ResearchMeSH KeywordsAgedCatheter AblationCohort StudiesColorectal NeoplasmsCombined Modality TherapyFemaleFollow-Up StudiesHumansLaparoscopyLiver NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPreoperative CareProspective StudiesRetrospective StudiesSurvival RateTomography, X-Ray ComputedTreatment OutcomeConceptsColorectal liver metastasesLaparoscopic radiofrequency ablationResectable colorectal liver metastasesRadiofrequency ablationResectable groupHepatic resectionLiver metastasesUnresectable groupMedian disease-free survivalComparable long-term survivalOutcomes of patientsDisease-free survivalKaplan-Meier methodLog-rank testLong-term survivalDiagnostic imaging studiesFavorable morbidityCRLM patientsPostoperative mortalityUnresectable diseaseMajor complicationsTumor numberResultsA totalSurgical oncologistsOutcome data