2021
SBRT for the Treatment of Isolated Local Recurrence of Resected Pancreatic Cancer
Morris L, Viehman J, Baclay J, Chang D, Kerans S, Molitoris J, Regine W, Johung K, Jethwa K, Neibart S, Jabbour S, Hallemeier C. SBRT for the Treatment of Isolated Local Recurrence of Resected Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e61. DOI: 10.1016/j.ijrobp.2021.07.408.Peer-Reviewed Original ResearchStereotactic body radiation therapyPancreatic ductal adenocarcinomaSurgical resectionFirst recurrenceCumulative incidenceLocal recurrenceDistant metastasisCompletion of SBRTTime of SBRTLow treatment-related toxicityMulti-institutional retrospective analysisDetails of recurrenceGrade 3 toxicityPrior treatment characteristicsInitial surgical resectionR0 resection rateTreatment-related toxicityRisk of progressionIsolated local recurrenceOverall survival estimatesLocal tumor controlSuperior mesenteric arteryBody radiation therapyKaplan-Meier modelOncologic surgical resection
2020
Radiation Therapy for Patients with Advanced Renal Cell Carcinoma
Miccio JA, Oladeru OT, Jun S, Johung KL. Radiation Therapy for Patients with Advanced Renal Cell Carcinoma. Urologic Clinics Of North America 2020, 47: 399-411. PMID: 32600541, DOI: 10.1016/j.ucl.2020.04.011.Peer-Reviewed Original ResearchConceptsStereotactic body radiation therapyRenal cell carcinomaAdvanced renal cell carcinomaCell carcinomaRadiation therapyMetastatic renal cell carcinomaExcellent local controlUse of radiotherapyBody radiation therapySelect patientsSurgical candidatesMetastatic sitesSurvival outcomesPrimary tumorImmune responseStereotactic radiosurgeryLocal controlPatientsMinimal toxicityCarcinomaTherapyFuture studiesPalliationRadiotherapyRadiosurgery
2019
When Surgery Is Not an Option in Renal Cell Carcinoma: The Evolving Role of Stereotactic Body Radiation Therapy.
Miccio J, Johung K. When Surgery Is Not an Option in Renal Cell Carcinoma: The Evolving Role of Stereotactic Body Radiation Therapy. Oncology 2019, 33: 167-73, 177. PMID: 31095714.Peer-Reviewed Original ResearchConceptsStereotactic body radiation therapyRenal cell carcinomaBody radiation therapyCell carcinomaRadiation therapyExcellent local control ratesMulti-fraction regimensExcellent local controlLocal control rateTreatment-related toxicityManagement of patientsSmall cohort sizeAdjuvant settingOligometastatic sitesNonsurgical patientsFraction radiationMetastatic sitesOnly palliationControl ratePrimary tumorTreatment approachesLocal controlCarcinomaTherapyPatients