2013
Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
Iwaya T, Fukagawa T, Suzuki Y, Takahashi Y, Sawada G, Ishibashi M, Kurashige J, Sudo T, Tanaka F, Shibata K, Endo F, Katagiri H, Ishida K, Kume K, Nishizuka S, Iinuma H, Wakabayashi G, Mori M, Sasako M, Mimori K. Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer. Clinical Cancer Research 2013, 19: 6438-6449. PMID: 24097871, DOI: 10.1158/1078-0432.ccr-12-3186.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedBiomarkers, TumorBone MarrowCell Line, TumorFemaleGastric MucosaGene Expression Regulation, NeoplasticHistonesHumansKaplan-Meier EstimateLymphatic MetastasisMaleMicroRNAsMiddle AgedMultivariate AnalysisNeoplasm StagingOligonucleotide Array Sequence AnalysisPrognosisProportional Hazards ModelsRNA InterferenceRNA, MessengerSequence Analysis, RNAStomach NeoplasmsTranscriptomeConceptsGastric cancer patientsStage IV patientsStage I patientsCancer patientsBone marrow samplesIV patientsBone marrowMiR-760 expressionPrimary tumor samplesPrimary tumorGastric cancerMiR-760I patientsPeripheral bloodMarrow samplesStage IV gastric cancer patientsAdvanced gastric cancer patientsTumor samplesLuciferase reporter assaysNoncancerous cellsRNA-seq analysisPrognostic markerMicroRNA-760Noncancerous mucosaPatients
2012
Molecular Marker Identification for Relapse Prediction in 5-FU-Based Adjuvant Chemotherapy in Gastric and Colorectal Cancers
Ishida K, Nishizuka SS, Chiba T, Ikeda M, Kume K, Endo F, Katagiri H, Matsuo T, Noda H, Iwaya T, Yamada N, Fujiwara H, Takahashi M, Itabashi T, Uesugi N, Maesawa C, Tamura G, Sugai T, Otsuka K, Koeda K, Wakabayashi G. Molecular Marker Identification for Relapse Prediction in 5-FU-Based Adjuvant Chemotherapy in Gastric and Colorectal Cancers. PLOS ONE 2012, 7: e43236. PMID: 22905237, PMCID: PMC3419205, DOI: 10.1371/journal.pone.0043236.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntimetabolites, AntineoplasticBiomarkers, TumorCell Line, TumorChemotherapy, AdjuvantCluster AnalysisColorectal NeoplasmsFluorouracilGene Expression Regulation, NeoplasticHumansImmunohistochemistryMAP Kinase Kinase 4Middle AgedPrognosisRecurrenceRNA, Small InterferingStomach NeoplasmsConceptsAdjuvant chemotherapyNF-κBCancer patientsTissue microarrayProtein expressionColorectal cancer patientsOverall survival rateGastrointestinal tract cancerGastric cancer patientsGastric cancer cell linesCell linesCancer cell linesJNK protein expressionR0 resectionTract cancerColorectal cancerImmunohistochemical examinationClinical significanceSurvival rateRelapse predictionBaseline expressionChemotherapyChemosensitivity markerPatientsGastric