2021
Network propagation-based prioritization of long tail genes in 17 cancer types
Mohsen H, Gunasekharan V, Qing T, Seay M, Surovtseva Y, Negahban S, Szallasi Z, Pusztai L, Gerstein MB. Network propagation-based prioritization of long tail genes in 17 cancer types. Genome Biology 2021, 22: 287. PMID: 34620211, PMCID: PMC8496153, DOI: 10.1186/s13059-021-02504-x.Peer-Reviewed Original ResearchConceptsCancer-relevant genesTail genesMobility genesNetwork propagation approachGenome-wide RNAiNetwork propagation methodCancer developmentPotential functional impactCancer cell survivalNew genesUnreported genesFunctional screeningCancer typesFunctional importanceCancer genesNovel potential therapeutic targetDriver genesCell survivalGenesMutational distributionsBiological interactionsPotential therapeutic targetFunctional impactGenomic alterationsInfrequent mutations
2013
Genomic alterations in matching primary tumors and metastasis in breast cancer.
Jiang T, Szekely B, Szasz A, Kluger Y, Kulka J, Pusztai L. Genomic alterations in matching primary tumors and metastasis in breast cancer. Journal Of Clinical Oncology 2013, 31: 1549-1549. DOI: 10.1200/jco.2013.31.15_suppl.1549.Peer-Reviewed Original ResearchPrimary tumorPrimary cancerBreast cancerMetastatic lesionsDisease historyExtensive prior therapyPrimary breast cancerLonger disease historyWhole-exome sequencingDifferent tumor sitesFunctional impactPrior therapyNucleotide variantsMetastasisPatientsTumor siteTumorsCancerNormal tissuesCancer samplesExome sequencingGenomic alterationsLesionsMore mutationsExon Kit