Heterogeneity of Breast Cancer among Patients and Implications for Patient Selection for Adjuvant Chemotherapy
Andre F, Pusztai L. Heterogeneity of Breast Cancer among Patients and Implications for Patient Selection for Adjuvant Chemotherapy. Pharmaceutical Research 2006, 23: 1951-1958. PMID: 16906452, DOI: 10.1007/s11095-006-9075-5.Peer-Reviewed Original ResearchConceptsAdjuvant chemotherapyBreast cancerPredictive valuePatient selectionSuch therapySingle biomarkerHeterogeneity of cancerChemotherapyPatientsCancerDaily practiceBiomarkersAbsolute effectLarge-scale genomic analysisFunctional pathwaysDistinct subclassesLarge populationHomogeneous subclassesTherapy