P3-17-01: ApoE and Its Receptors (LRP8, VLDLR) Function as Growth Signals for Triple-Negative Breast Cancer and Represent a Novel Therapeutic Target.
Shiang C, Qi Y, Wang B, Broom B, Pusztai L. P3-17-01: ApoE and Its Receptors (LRP8, VLDLR) Function as Growth Signals for Triple-Negative Breast Cancer and Represent a Novel Therapeutic Target. Cancer Research 2011, 71: p3-17-01-p3-17-01. DOI: 10.1158/0008-5472.sabcs11-p3-17-01.Peer-Reviewed Original ResearchTriple-negative breast cancerER-negative cellsBreast cancerHuman epidermal growth factor 2 receptorReceptor systemAbstract Triple-negative breast cancerStimulatory effectCell linesEarly-onset breast cancerHuman triple-negative breast cancerER-negative cell linesExpression of estrogenReceptor-positive cancersER-positive cellsOnset breast cancerNovel therapeutic targetBreast cancer cell linesBreast cancer tissuesInflammatory signaling pathwaysMAPK/ERK pathwayPreferential growth inhibitionApoE4 expressionCancer cell linesTreatment optionsGrowth factor 2 receptor