Total RNA yield and microarray gene expression profiles from fine‐needle aspiration biopsy and core‐needle biopsy samples of breast carcinoma
Symmans WF, Ayers M, Clark EA, Stec J, Hess KR, Sneige N, Buchholz TA, Krishnamurthy S, Ibrahim NK, Buzdar AU, Theriault RL, Rosales MF, Thomas ES, Gwyn KM, Green MC, Syed AR, Hortobagyi GN, Pusztai L. Total RNA yield and microarray gene expression profiles from fine‐needle aspiration biopsy and core‐needle biopsy samples of breast carcinoma. Cancer 2003, 97: 2960-2971. PMID: 12784330, DOI: 10.1002/cncr.11435.Peer-Reviewed Original ResearchConceptsGene expression profilesTranscriptional profilesExpression profilesFine-needle aspiration biopsyGenomic databasesStromal gene expressionGene expressionTotal RNA yieldTotal RNABreast carcinomaTumor cell populationSubset of genesCDNA microarray analysisStromal cellsBiopsy samplesGene expression profilingCell populationsMicroscopic cell countsRNA yieldAspiration biopsyGenomic studiesTranscriptional profilingCDNA microarrayNonlymphoid stromal cellsExpression profiling