High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients
Holder AM, Gonzalez-Angulo AM, Chen H, Akcakanat A, Do KA, Fraser Symmans W, Pusztai L, Hortobagyi GN, Mills GB, Meric-Bernstam F. High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients. Breast Cancer Research And Treatment 2012, 137: 319-327. PMID: 23208590, PMCID: PMC3556743, DOI: 10.1007/s10549-012-2354-4.Peer-Reviewed Original ResearchConceptsRelapse-free survivalShorter relapse-free survivalBreast cancerOverall survivalPatient ageMultivariable analysisClinical stageSCD1 levelsSCD1 expressionTumor subtypesStearoyl-CoA desaturase 1 expressionTriple-negative breast cancerMartingale residual plotsPrimary breast cancerSurvival of patientsBreast cancer patientsClinical pathologic characteristicsTumor clinical stageDesaturase 1 expressionBreast cancer subtypesBreast cancer cell linesExpression levelsRole of SCD1Fine needle aspiratesOverexpression of SCD1