2003
Estrogen Receptors and Distinct Patterns of Breast Cancer Relapse
Hess KR, Pusztai L, Buzdar AU, Hortobagyi GN. Estrogen Receptors and Distinct Patterns of Breast Cancer Relapse. Breast Cancer Research And Treatment 2003, 78: 105-118. PMID: 12611463, DOI: 10.1023/a:1022166517963.Peer-Reviewed Original ResearchConceptsER-negative statusER-positive tumorsSite of recurrenceBreast cancer deathsFirst recurrenceER statusTumor recurrenceCancer deathClinical behaviorAdjuvant therapy protocolsOperable stage IIER-negative cancersER-positive statusRate of recurrenceBreast cancer relapseHigh rateMenopausal statusTumor burdenRecurrence rateBreast cancerEstrogen receptorCancer relapseRecurrencePatientsStage II
1999
Relapse after complete response to anthracycline‐based combination chemotherapy in metastatic breast cancer
Pusztai L, Asmar L, Smith T, Hortobagyi G. Relapse after complete response to anthracycline‐based combination chemotherapy in metastatic breast cancer. Breast Cancer Research And Treatment 1999, 55: 1-8. PMID: 10472774, DOI: 10.1023/a:1006161906667.Peer-Reviewed Original ResearchConceptsAnthracycline-based combination chemotherapyComplete clinical responseDisease-free intervalMetastatic breast cancerInitial disease-free intervalSecond relapseFirst relapseCombination chemotherapyCR durationMedian survivalBreast cancerShorter CR durationSite of recurrenceLength of survivalMore frequent recurrenceClinical characteristicsClinical responseFirst recurrenceMetastatic diseaseVisceral sitesComplete responseClinical featuresMetastatic sitesSubsequent therapySecond recurrence