2016
Bone density screening in postmenopausal women with early-stage breast cancer on aromatase inhibitors.
Stratton J, Hu X, Soulos P, Davidoff A, Pusztai L, Gross C, Mougalian S. Bone density screening in postmenopausal women with early-stage breast cancer on aromatase inhibitors. Journal Of Clinical Oncology 2016, 34: 6599-6599. DOI: 10.1200/jco.2016.34.15_suppl.6599.Peer-Reviewed Original Research
2015
Uptake of exemestane chemoprevention in postmenopausal women at increased risk for breast cancer
Aktas B, Sorkin M, Pusztai L, Hofstatter EW. Uptake of exemestane chemoprevention in postmenopausal women at increased risk for breast cancer. European Journal Of Cancer Prevention 2015, 25: 3-8. PMID: 25642790, PMCID: PMC4885537, DOI: 10.1097/cej.0000000000000124.Peer-Reviewed Original ResearchConceptsCancer prevention clinicSelective estrogen receptor modulatorsPostmenopausal womenEstrogen receptor modulatorsChemoprevention uptakePrevention clinicReceptor modulatorsBreast cancer chemopreventionRetrospective chart reviewSerious side effectsChemoprevention medicationsChemopreventive optionChart reviewMean ageAromatase inhibitorsBreast cancerBone densityStudy populationCancer chemopreventionGeneral populationExemestaneSide effectsChemopreventionClinicWomenChemotherapy and the recurrence score—results as expected?
Pusztai L. Chemotherapy and the recurrence score—results as expected? Nature Reviews Clinical Oncology 2015, 12: 690-692. PMID: 26552957, DOI: 10.1038/nrclinonc.2015.191.Peer-Reviewed Original ResearchSystematic Approach to Providing Breast Cancer Survivors With Survivorship Care Plans: A Feasibility Study
Bulloch KJ, Irwin ML, Chagpar AB, Pusztai L, Killelea BK, Horowitz NR, Hofstatter EW, Abu-Khalaf MM, DiGiovanna M, Chung GG, Sanft TB. Systematic Approach to Providing Breast Cancer Survivors With Survivorship Care Plans: A Feasibility Study. JCO Oncology Practice 2015, 11: e170-e176. PMID: 25784577, DOI: 10.1200/jop.2015.005173.Peer-Reviewed Original ResearchConceptsAdverse eventsBreast cancerPostoperative visitPatient knowledgeEligible participantsSurvivorship care plansBreast cancer survivorsPotential adverse eventsAge 18 yearsRisk of leukemiaFuture adverse eventsElectronic medical recordsKnowledge of tumorsRoutine followPostoperative appointmentsCancer survivorsMedical recordsSurgical clinicTreatment completionCare plansStage IMcNemar testCancerVisitsWomen
2011
Open label, randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC (T-FEC) versus the combination of paclitaxel and RAD001 followed by FEC (TR-FEC) in women with triple receptor-negative breast cancer (TNBC).
Gonzalez-Angulo A, Green M, Murray J, Palla S, Koenig K, Brewster A, Valero V, Ibrahim N, Moulder S, Litton J, Crawford D, Flores P, Dryden M, Symmans W, Giordano S, Pusztai L, Buzdar A, Mills G, Hortobagyi G, Meric-Bernstam F. Open label, randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC (T-FEC) versus the combination of paclitaxel and RAD001 followed by FEC (TR-FEC) in women with triple receptor-negative breast cancer (TNBC). Journal Of Clinical Oncology 2011, 29: 1016-1016. DOI: 10.1200/jco.2011.29.15_suppl.1016.Peer-Reviewed Original Research
2007
Breast Cancer
Ross J, Linette G, Stec J, Clark E, Ayers M, Symmans F, Hortobagyi G, Pusztai L. Breast Cancer. 2007, 269-278. DOI: 10.1007/978-0-387-33227-7_24.Peer-Reviewed Original ResearchBreast cancerInvasive breast cancerCurrent incidence ratesAmerican womenGenetic predisposition testingMicrometastasis detectionSitu diseaseClinical managementIncidence rateField of pharmacogenomicsRNA expression profilingNew casesPredisposition testingCancerMolecular pathologyBiomarker assaysSerum diagnosticsDiseaseWomenExpression profilingFuture assaysAssaysPathology
2004
Assessment of Response to Neoadjuvant Chemotherapy in Breast Cancer: Imaging Considerations
Whitman G, Iyer R, Reeve C, Patel P, Phelps M, Pusztai L. Assessment of Response to Neoadjuvant Chemotherapy in Breast Cancer: Imaging Considerations. Seminars In Breast Disease 2004, 7: 61-74. DOI: 10.1053/j.sembd.2005.01.005.Peer-Reviewed Original ResearchNeoadjuvant chemotherapyMagnetic resonance imagingPositron emission tomographyBreast cancerAssessment of responseCurrent imaging techniquesPreoperative chemotherapyTumor bedClinical examinationChemotherapyFavorable responseResonance imagingEmission tomographyImaging considerationsCancerImaging techniquesMetal markersResponsePatientsSestamibiSonographyTherapyWomenPharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinoma
Pusztai L, Gregory BW, Baggerly KA, Peng B, Koomen J, Kuerer HM, Esteva FJ, Symmans WF, Wagner P, Hortobagyi GN, Laronga C, Semmes OJ, Wright GL, Drake RR, Vlahou A. Pharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinoma. Cancer 2004, 100: 1814-1822. PMID: 15112261, DOI: 10.1002/cncr.20203.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorBiopsy, NeedleBreast NeoplasmsCase-Control StudiesChemotherapy, AdjuvantCyclophosphamideDoxorubicinDrug Administration ScheduleFemaleFluorouracilHumansMastectomyMiddle AgedNeoadjuvant TherapyNeoplasm StagingPaclitaxelPostoperative CarePreoperative CareProteomicsRisk AssessmentSensitivity and SpecificitySurvival AnalysisTreatment OutcomeConceptsBreast carcinomaHealthy womenPreoperative chemotherapyFinal tumor responseSubset of patientsDay 3 posttreatmentAdjuvant chemotherapyPostoperative chemotherapyCyclophosphamide chemotherapyFAC chemotherapyMicrometastatic diseasePaclitaxel chemotherapyNormal womenTumor responsePlasma profilesHealthy volunteersChemotherapyPatientsStage ICarcinomaDay 0Single courseWomenPlasma samplesCandidate markers