2016
Clinical events in a large prospective cohort of children with sickle cell disease in Nagpur, India: evidence against a milder clinical phenotype in India
Jain D, Arjunan A, Sarathi V, Jain H, Bhandarwar A, Vuga M, Krishnamurti L. Clinical events in a large prospective cohort of children with sickle cell disease in Nagpur, India: evidence against a milder clinical phenotype in India. Pediatric Blood & Cancer 2016, 63: 1814-1821. PMID: 27279568, DOI: 10.1002/pbc.26085.Peer-Reviewed Original ResearchConceptsSickle cell diseaseRate of painAcute chest syndromeRate of complicationsNewborn screenCell diseaseChest syndromeFrequent complicationSevere anemiaSplenic sequestrationClinical phenotypeLarge single-center studyMore frequent complicationsSingle-center studyLarge prospective cohortPediatric SCD patientsPhenotypes of SCDMilder clinical phenotypeProspective cohortSCD patientsClinical eventsComplicationsSCD phenotypeCooperative StudyEvent rates
2010
Prolonged QTc Interval Is Common In Patients with Sickle Cell Disease and Has An Inverse Relationship to Hemoglobin and Hematocrit: Results From CSSCD
Goel R, Rajderkar S, Padman R, Krishnamurti L. Prolonged QTc Interval Is Common In Patients with Sickle Cell Disease and Has An Inverse Relationship to Hemoglobin and Hematocrit: Results From CSSCD. Blood 2010, 116: 2675. DOI: 10.1182/blood.v116.21.2675.2675.Peer-Reviewed Original ResearchSickle cell diseaseProlonged QTcCardiac deathSCD patientsCell diseaseProlonged QTc intervalPremature cardiac deathSudden cardiac deathMultivariate logistic regressionYears of ageLead EKGEchocardiographic characteristicsHbSS patientsClinical courseQTc intervalProspective studyClinical centersHigh riskPatientsQTcStudy subjectsEstablished markerCooperative StudyLogistic regressionNational Institute