2022
Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates
Day J, Takemoto C, Sharathkumar A, Makhani S, Gupta A, Bitner S, Josephson C, Bloch E, Tobian A, Krishnamurti L, Goel R. Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative estimates. Haemophilia 2022, 28: 532-541. PMID: 35412659, PMCID: PMC9540439, DOI: 10.1111/hae.14557.Peer-Reviewed Original ResearchConceptsNationwide Inpatient SampleHealthcare utilizationPrevalence of comorbiditiesAge-related comorbiditiesCentral line infectionsInpatient discharge databaseOverall mortality rateCatheter-related infectionsHealthcare utilization patternsMedian hospital chargesICD-10 codesRepresentative estimatesCause admissionsCause hospitalizationAdult PWHAssociated comorbidityCommon comorbiditiesHospitalized patientsMedian ageContemporary cohortHospital burdenHospital chargesDischarge databaseInpatient SampleLine infections
2019
Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Representative Estimates and a Comparative Analysis
Gupta A, Hannan A, Maini R, Bitner S, Stone S, Regmi M, Tobian A, Josephson C, Krishnamurti L, Takemoto C, Goel R. Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Representative Estimates and a Comparative Analysis. Blood 2019, 134: 4711. DOI: 10.1182/blood-2019-123161.Peer-Reviewed Original ResearchCongestive heart failureNationwide Inpatient SampleMedian hospital chargesHepatitis CMedian ageHIV/AIDSHospital dischargeInpatient mortalityHeart failureCommon diagnosisHealthcare utilizationHaemophilia patientsHospital chargesMortality rateHemophilia AUtilization Project Nationwide Inpatient SampleYounger ageCommon discharge diagnosesMost hemophilia patientsNon-bleeding complicationsInpatient mortality rateHepatitis C casesCentral line infectionsCoronary artery diseaseInsurance coverage
2018
Platelet transfusion practices in immune thrombocytopenia related hospitalizations
Goel R, Chopra S, Tobian A, Ness P, Frank S, Cushing M, Vasovic L, Kaicker S, Takemoto C, Josephson C, Nellis M, Bussel J, Krishnamurti L. Platelet transfusion practices in immune thrombocytopenia related hospitalizations. Transfusion 2018, 59: 169-176. PMID: 30520045, DOI: 10.1111/trf.15069.Peer-Reviewed Original ResearchConceptsPlatelet transfusion practicesImmune thrombocytopeniaPlatelet transfusionsNational Inpatient SampleAdmission diagnosisTransfusion practiceCurrent guidelinesHigher mean total hospital chargesMean total hospital chargesSmall bed size hospitalsMultivariable logistic regression analysisPayer inpatient databasePrimary admission diagnosisSurgery/procedureTotal hospital chargesMajor operative proceduresLogistic regression analysisNon-teaching hospitalsInvasive surgical proceduresHospital mortalityMultivariable adjustmentITP patientsClinical outcomesRelated hospitalizationsHospital charges
2012
Mortality, health care utilization and associated diagnoses in hospitalized patients with haemophilia in the United States: first reported nationwide estimates
GOEL R, KRISHNAMURTI L. Mortality, health care utilization and associated diagnoses in hospitalized patients with haemophilia in the United States: first reported nationwide estimates. Haemophilia 2012, 18: 688-692. PMID: 22500777, DOI: 10.1111/j.1365-2516.2012.02774.x.Peer-Reviewed Original ResearchConceptsNational Inpatient SampleCentral line infectionsHospital mortalityHospital dischargeLine infectionsHemophilia AMean hospital chargesCause of hospitalizationHealth care utilizationGeneral male populationDiagnosis of hemophiliaAge-related illnessesStratified probability sampleHepatitis CRespiratory failureHeart failureIntraventricular hemorrhageMedian ageAge of mortalityCare utilizationHospital chargesIntracranial hemorrhageNeonatal periodPediatric deathsHepatic coma
2010
Burden of In-Hospital Care of Thrombotic Microangiopathies In the United States
Gupta A, Krishnamurti L. Burden of In-Hospital Care of Thrombotic Microangiopathies In the United States. Blood 2010, 116: 2559. DOI: 10.1182/blood.v116.21.2559.2559.Peer-Reviewed Original ResearchNationwide Inpatient SampleThrombotic microangiopathyHealth care utilizationRelated hospital admissionsHealthcare utilizationHospital dischargeHospital admissionCare utilizationHospital chargesTherapeutic plasmapheresisAge groupsFrequent healthcare encountersIn-Hospital CarePayer inpatient databaseClinical Modification codesAverage hospital chargesBurden of careNational dataFirst national dataStratified probability sampleU.S. community hospitalsTotal hospitalizationsFrequent hospitalizationsInpatient DatabaseMean duration