2021
Hematopoietic Cell Transplantation for Sickle Cell Disease
Krishnamurti L. Hematopoietic Cell Transplantation for Sickle Cell Disease. Frontiers In Pediatrics 2021, 8: 551170. PMID: 33469520, PMCID: PMC7813811, DOI: 10.3389/fped.2020.551170.Peer-Reviewed Original ResearchHematopoietic cell transplantationSickle cell diseaseAutologous hematopoietic progenitor cellsCell transplantationHematopoietic progenitor cellsDisease manifestationsCell diseaseRelated donor hematopoietic cell transplantationDonor hematopoietic cell transplantationEarly phase clinical trialsHaploidentical related donorsIntent of cureProgenitor cellsIschemic tissue damageLong-term ameliorationHaploidentical donorsEndothelial dysfunctionHLA-identicalLate complicationsRed blood cellsUnrelated HLAOrgan dysfunctionRelated donorsUnrelated donorsSCD patients
2016
Development, Implementation, and Testing of a Web Based Decision Aid for Facilitating Shared Decision Making for Disease Modifying Therapies for Sickle Cell Disease
Krishnamurti L, Ross D, Bakshi N, Khemani K, Sinha C, Loewenstein G. Development, Implementation, and Testing of a Web Based Decision Aid for Facilitating Shared Decision Making for Disease Modifying Therapies for Sickle Cell Disease. Blood 2016, 128: 5919. DOI: 10.1182/blood.v128.22.5919.5919.Peer-Reviewed Original ResearchSickle cell diseaseHematopoietic stem cell transplantationClinical trialsCell diseaseClinical decisionPatients/family membersFinal decision aidOttawa Decision Support FrameworkDisease-Modifying TherapiesChronic blood transfusionsStem cell transplantationRandomized clinical trialsDecision aidMix of patientsEligible patientsModifying therapiesLate complicationsBlood transfusionFavorable patientsSubstantial morbidityCell transplantationQualitative interviewsPhysicians' perceptionsPremature mortalitySubstantial burden