2007
Unrelated cord blood transplantation in children with sickle cell disease: Review of four‐center experience
Adamkiewicz T, Szabolcs P, Haight A, Baker K, Staba S, Kedar A, Chiang K, Krishnamurti L, Boyer M, Kurtzberg J, Wagner J, Wingard J, Yeager A. Unrelated cord blood transplantation in children with sickle cell disease: Review of four‐center experience. Pediatric Transplantation 2007, 11: 641-644. PMID: 17663687, DOI: 10.1111/j.1399-3046.2007.00725.x.Peer-Reviewed Original ResearchConceptsUnrelated cord blood transplantationReduced-intensity regimensPrimary graft failureCord blood transplantationStable mixed chimerismSickle cell diseaseBlood transplantationGraft failureMyeloablative regimensMixed chimerismGrade IIICell diseaseViral infectionGVHDUCBTRegimensPatientsEngraftmentInfectionChildrenTransplantationStrokeChimerismEngraftDisease
2005
Mixed Hematopoietic Chimerism for Sickle Cell Disease Prevents Intravascular Hemolysis and Corrects Biomarkers of Endothelial Function.
Wu C, Krishnamurti L, Gladwin M, Biernacki M, Rogers S, Wang X, Zahrieh D, Antin J, Ritz J. Mixed Hematopoietic Chimerism for Sickle Cell Disease Prevents Intravascular Hemolysis and Corrects Biomarkers of Endothelial Function. Blood 2005, 106: 2333. DOI: 10.1182/blood.v106.11.2333.2333.Peer-Reviewed Original ResearchSickle cell diseaseMixed hematopoietic chimerismStem cell transplantationEndothelial functionIntravascular hemolysisMixed chimerismPulmonary hypertensionDonor engraftmentCell transplantationVascular functionHematopoietic chimerismNonmyeloablative allogeneic stem cell transplantationChronic end-organ damageAllogeneic stem cell transplantationEnd-organ injuryExperienced graft rejectionEnd-organ damageEnd-organ toxicityPre-transplant levelsDonor cell engraftmentChronic intravascular hemolysisSuccess of therapyFree Hb concentrationEndothelial dysfunctionGraft rejection