2024
Artificial intelligence applied to electrocardiographic images for the risk stratification of cancer therapeutics-related cardiac dysfunction
Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial intelligence applied to electrocardiographic images for the risk stratification of cancer therapeutics-related cardiac dysfunction. European Heart Journal 2024, 45: ehae666.3190. DOI: 10.1093/eurheartj/ehae666.3190.Peer-Reviewed Original ResearchCancer therapeutics-related cardiac dysfunctionImmune checkpoint inhibitorsGlobal longitudinal strainLeft ventricular systolic dysfunctionNon-Hodgkin's lymphomaCardiac dysfunctionAI-ECGNegative control analysesAssociated with higher incidenceVentricular systolic dysfunctionCohort of patientsRisk stratification strategiesCheckpoint inhibitorsTrastuzumab exposureSystolic dysfunctionRisk stratificationBreast cancerRisk biomarkersSecondary outcomesLongitudinal strainStratification strategiesTrastuzumabPatientsHigher incidenceAnthracyclines
2023
Advances in Coronary Computed Tomographic Angiographic Imaging of Atherosclerosis for Risk Stratification and Preventive Care
Bienstock S, Lin F, Blankstein R, Leipsic J, Cardoso R, Ahmadi A, Gelijns A, Patel K, Baldassarre L, Hadley M, LaRocca G, Sanz J, Narula J, Chandrashekhar Y, Shaw L, Fuster V. Advances in Coronary Computed Tomographic Angiographic Imaging of Atherosclerosis for Risk Stratification and Preventive Care. JACC Cardiovascular Imaging 2023, 16: 1099-1115. PMID: 37178070, DOI: 10.1016/j.jcmg.2023.02.002.Peer-Reviewed Original ResearchConceptsCoronary Computed Tomography AngiographyCoronary artery diseaseAtherosclerotic plaquesArtery diseaseRisk stratificationPreventive carePlaque volumeHigh-risk plaque featuresNonobstructive coronary artery diseaseCoronary CTAMeasurements of atherosclerosisEffective risk stratificationHigh-risk patientsTotal plaque volumeComputed tomography angiographyPatient-specific factorsCoronary artery dimensionsIntravascular ultrasound measurementsHealth care systemCoronary dominanceCardiovascular preventionPatient subsetsPlaque featuresArtery sizeTomography angiography
2021
Left atrial evaluation by cardiovascular magnetic resonance: sensitive and unique biomarkers
Peters DC, Lamy J, Sinusas AJ, Baldassarre LA. Left atrial evaluation by cardiovascular magnetic resonance: sensitive and unique biomarkers. European Heart Journal - Cardiovascular Imaging 2021, 23: 14-30. PMID: 34718484, PMCID: PMC8685602, DOI: 10.1093/ehjci/jeab221.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementAtrial fibrillationCardiovascular magnetic resonanceDiastolic dysfunctionEjection fractionAF recurrenceAtrial fibrosisNew-onset atrial fibrillationPost-operative atrial fibrillationLongitudinal LA strainExtent of fibrosisLong-axis cine imagesCine imagesAtrial imagingCardiovascular eventsLA volumeRisk stratificationAF subjectsPrognostic informationHypertrophic cardiomyopathyLA strainGadolinium enhancementSensitive markerAblation proceduresMagnetic resonance